Results 41 to 50 of about 922,998 (286)

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen   +23 more
wiley   +1 more source

A PRSZT Registry Analysis of Prognostic Factors Influencing Survival and Relapse Rates After Second Allogeneic Hematopoietic Stem Cell Transplantation in Pediatric Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT A second allogeneic (allo‐)hematopoietic stem cell transplantation (HSCT2) is a potential curative option for pediatric patients with acute lymphoblastic leukemia (ALL) following relapse after first allogeneic transplantation (HSCT1), but its efficacy is limited by high relapse rates and transplant‐related toxicity in highly pretreated ...
Ava Momm   +10 more
wiley   +1 more source

Global optimization of complex optical structures using Baysian optimization based on Gaussian processes

open access: yes, 2017
Numerical simulation of complex optical structures enables their optimization with respect to specific objectives. Often, optimization is done by multiple successive parameter scans, which are time consuming and computationally expensive.
Burger, S.   +3 more
core   +1 more source

An Adaptive Whale Optimization Algorithm Using Gaussian Distribution Strategies and Its Application in Heterogeneous UCAVs Task Allocation

open access: yesIEEE Access, 2019
To overcome the defect of whale optimization algorithm (WOA) being easily fallen into local optimum caused by the ill-distribution of solutions, this paper explores an adaptive WOA variant using Gaussian distribution strategies (GDSs), named GDS-WOA.
Yintong Li   +3 more
doaj   +1 more source

Circle Search Algorithm: A Geometry-Based Metaheuristic Optimization Algorithm

open access: yesMathematics, 2022
This paper presents a novel metaheuristic optimization algorithm inspired by the geometrical features of circles, called the circle search algorithm (CSA).
Mohammed H. Qais   +5 more
doaj   +1 more source

Sparse sum-of-squares (SOS) optimization: A bridge between DSOS/SDSOS and SOS optimization for sparse polynomials

open access: yes, 2018
Optimization over non-negative polynomials is fundamental for nonlinear systems analysis and control. We investigate the relation between three tractable relaxations for optimizing over sparse non-negative polynomials: sparse sum-of-squares (SSOS ...
Fantuzzi, Giovanni   +2 more
core   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

open access: yesFEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Connectivity, Transmission Power, and Lifetime Optimization in Asymmetric Networks: A Distributed Approach

open access: yesIEEE Access, 2018
One of the fundamental challenges of deploying sensor networks in applications, such as environmental monitoring and surveillance, is power management in the presence of various constraints.
Milad Esmaeilpour   +2 more
doaj   +1 more source

Resource Efficiency and Thermal Comfort of 3D Printable Concrete Building Envelopes Optimized by Performance Enhancing Insulation: A Numerical Study

open access: yesEnergies, 2022
3D concrete printing has gained tremendous popularity as a promising technique with the potential to remarkably push the boundaries of conventional concrete technology.
Blessing Onyeche Ayegba   +4 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

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