Results 41 to 50 of about 66,031 (239)

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Diffusion mechanism of pulsating seepage grouting slurry with power-law fluid considering interval distribution

open access: yesYantu gongcheng xuebao, 2018
Although the pulsating grouting technology has been widely used, the diffusion mechanism of grout under fluctuating pressure is far behind the engineering practice.
ZHANG Cong 1, LIANG Jin-wei 2, YANG Jun-sheng 1, ZHANG Gui-jin 3, XIE Yi-peng 1, YE Xin-tian 1
doaj   +1 more source

Identification of the plant mitochondrial OrfX protein: A mass spectrometry approach

open access: yesFEBS Letters, EarlyView.
The mitochondrial genome of plants contains an open reading frame, orfx, which encodes a rare protein that has so far escaped mass spectrometric detection. The protein resembles the c‐subunit of bacterial twin‐arginine‐motif‐dependent protein translocases (TatC).
Matthias Döring   +3 more
wiley   +1 more source

All-Glass Single-Mode Leakage Channel Microstructured Optical Fibers with Large Mode Area and Low Bending Loss

open access: yesPhotonics, 2023
The paper presents the results of theoretical and experimental studies of all-glass leakage channel microstructured optical fibers (MOFs) with a large mode area and low bending losses. These MOFs contain two layers of fluorine-doped silica glass elements
Alexander Denisov   +6 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Laminar Free Convection In Horizontal Annulus Filled With Glass Beads And With Annular Fins On The Inner Cylinder

open access: yesJournal of Engineering, 2023
An experimental and numerical study has been carried out to investigate the heat transfer by natural convection and radiation in a two dimensional annulus enclosure filled with porous media (glass beads) between two horizontal concentric cylinders.
Manal Hadi Saleh, Ahmed Mohsen Katea
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Analytical solution and numerical simulation of the liquid nitrogen freezing-temperature field of a single pipe

open access: yesAIP Advances, 2018
Artificial liquid nitrogen freezing technology is widely used in urban underground engineering due to its technical advantages, such as simple freezing system, high freezing speed, low freezing temperature, high strength of frozen soil, and absence of ...
Haibing Cai   +3 more
doaj   +1 more source

Study on the Instability Mechanism and Grouting Reinforcement Repair of Large-Scale Underground Stopes

open access: yesAdvances in Civil Engineering, 2020
The environmental conditions due to unreasonable mining in underground stopes, the slurry diffusion mechanism in the grouting reinforcement of a stope within its influence, the causes of large-scale instability collapse, and the catastrophic stope ...
Chengyu Xie, Nan Jia, Liwen He
doaj   +1 more source

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