Results 51 to 60 of about 624,709 (272)

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Accretion Rates of Planetesimals by Protoplanets Embedded in Nebular Gas

, 2009
When protoplanets growing by accretion of planetesimals have atmospheres, small planetesimals approaching the protoplanets lose their energy by gas drag from the atmospheres, which leads them to be captured within the Hill sphere of the protoplanets.
Benvenuto, Bodenheimer, Chambers, Chambers, Chambers, Dones, D’Angelo, Fortney, Greenzweig, Greenzweig, Hubickyj, Ida, Ida, Ida, Ikoma, Inaba, Inaba, Inaba, Kary, Kary, Keiji Ohtsuki, Kokubo, Kokubo, Korycansky, Masset, Mizuno, Movshovitz, Nakazawa, Nishida, Ohtsuki, Ohtsuki, Ohtsuki, Podolak, Pollack, Pollack, Rafikov, Sasaki, Stevenson, Takayuki Tanigawa, Tanaka, Tanaka, Ward, Ward, Wetherill, Wetherill, Ćuk   +45 more
core   +1 more source

On acoustic cavitation of slightly subcritical bubbles [PDF]

, 1998
The classical Blake threshold indicates the onset of quasistatic evolution leading to cavitation for gas bubbles in liquids. When the mean pressure in the liquid is reduced to a value below the vapor pressure, the Blake analysis identifies a critical ...
Harkin, Anthony, Kaper, Tasso J., Nadim, Ali   +2 more
core   +3 more sources

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Diffusion mechanism of pulsating seepage grouting slurry with power-law fluid considering interval distribution

Yantu gongcheng xuebao, 2018
Although the pulsating grouting technology has been widely used, the diffusion mechanism of grout under fluctuating pressure is far behind the engineering practice.
ZHANG Cong 1, LIANG Jin-wei 2, YANG Jun-sheng 1, ZHANG Gui-jin 3, XIE Yi-peng 1, YE Xin-tian 1
doaj   +1 more source

Minimum Radii of Super-Earths: Constraints from Giant Impacts

, 2010
The detailed interior structure models of super-Earth planets show that there is degeneracy in the possible bulk compositions of a super-Earth at a given mass and radius, determined via radial velocity and transit measurements, respectively. In addition,
Adams, Agnor, Borucki, Fortney, Grasset, Ida, Marcus, Masset, Melnick, Petaev, Sasselov, Stewart, Valencia   +12 more
core   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

All-Glass Single-Mode Leakage Channel Microstructured Optical Fibers with Large Mode Area and Low Bending Loss

Photonics, 2023
The paper presents the results of theoretical and experimental studies of all-glass leakage channel microstructured optical fibers (MOFs) with a large mode area and low bending losses. These MOFs contain two layers of fluorine-doped silica glass elements
Alexander Denisov, Vladislav Dvoyrin, Alexey Kosolapov, Mikhail Likhachev, Vladimir Velmiskin, Sergey Zhuravlev, Sergey Semjonov   +6 more
doaj   +1 more source

Developmental, Neuroanatomical and Cellular Expression of Genes Causing Dystonia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Dystonia is one of the most common movement disorders, with variants in multiple genes identified as causative. However, an understanding of which developmental stages, brain regions, and cell types are most relevant is crucial for developing relevant disease models and therapeutics.
Darren Cameron, Nicholas E. Clifton, Daniel Cabezas de la Fuente, Peter Holmans, Nicholas J. Bray, Kathryn J. Peall   +5 more
wiley   +1 more source