Results 51 to 60 of about 7,359,195 (249)
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Yantu gongcheng xuebao, 2018 Although the pulsating grouting technology has been widely used, the diffusion mechanism of grout under fluctuating pressure is far behind the engineering practice.
ZHANG Cong 1, LIANG Jin-wei 2, YANG Jun-sheng 1, ZHANG Gui-jin 3, XIE Yi-peng 1, YE Xin-tian 1
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Reverse Inequalities for the Numerical Radius of Linear Operators in Hilbert Spaces [PDF]
, 2005 Some elementary inequalities providing upper bounds for the difference of the norm and the numerical radius of a bounded linear operator on Hilbert spaces under appropriate conditions are ...
Sever S. Dragomir, Dragomir, Sever S
core +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Journal of Engineering, 2023 An experimental and numerical study has been carried out to investigate the heat transfer by natural convection and radiation in a two dimensional annulus enclosure filled with porous media (glass beads) between two horizontal concentric cylinders.
Manal Hadi Saleh, Ahmed Mohsen Katea
doaj +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
AIP Advances, 2018 Artificial liquid nitrogen freezing technology is widely used in urban underground engineering due to its technical advantages, such as simple freezing system, high freezing speed, low freezing temperature, high strength of frozen soil, and absence of ...
Haibing Cai +3 more
doaj +1 more source
Advances in Civil Engineering, 2020 The environmental conditions due to unreasonable mining in underground stopes, the slurry diffusion mechanism in the grouting reinforcement of a stope within its influence, the causes of large-scale instability collapse, and the catastrophic stope ...
Chengyu Xie, Nan Jia, Liwen He
doaj +1 more source
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source