Results 121 to 130 of about 2,436,536 (336)
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Spatial Numerical Range of Operators on Weighted Hardy Spaces
International Journal of Mathematics and Mathematical Sciences, 2011 We consider the spatial numerical range of operators on weighted Hardy spaces and give conditions for closedness of numerical range of compact operators.
Abdolaziz Abdollahi +1 more
doaj +1 more source
Condition for the higher rank numerical range to be non-empty [PDF]
, 2008 Chi-Kwong Li +5 more
openalex +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Scientific DataRangelands are extensive ecosystems, providing important ecosystem services while undergoing continuous change. As a result, improved monitoring technologies can help better characterize vegetation change. Satellite remote sensing has proven effective in
Brady W. Allred +28 more
doaj +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
A generalization of the 0-numerical range
Glasnik Matematicki, 2004 Let H be a Hilbert space. Given a bounded linear operator A on H, we describe the set R^n(A)={;V*AW:V*V=W*W=I_n, V*W=0};. It is shown that the closed matricial convex hull of R^n(A) is a closed ball of radius min||A-\lambda I|| centered at origin.
openaire +4 more sources
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Numerical studies of a one-dimensional three-spin spin-glass model with long-range interactions [PDF]
, 2010 Derek Larson +3 more
openalex +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source