Results 121 to 130 of about 419,543 (296)

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

Molecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu, Jianchao Wang, Fuqing Chen, Xuefeng Wang, Bin Lan, Ruyi Fu, Hong Wen, Fangfang Chen, Wei Hong, Tian‐Yu Tang, Ying He, Gang Chen, Jianyin Zhou, Hai‐Long Piao, Di Chen, Shu‐Yong Lin   +15 more
wiley   +1 more source

Closed numerical ranges

, 2018
Let $ x=(x_{n})_{n} $ be a bounded complex sequence and let $M_{x} = \sup_n |x_n|$. By using a normaloid operator related to the sequence $ x=(x_{n})_{n} $, we prove that $$ \sup_{ \in \mathbb{C}, | | \leq M_x} \sup_n |x_n+ | = 2M_x.$$
Baghdad, Abderrahim, kaadoud, Mohamed Chraibi   +1 more
openaire   +2 more sources

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Numerical range of tensor product of operators in semi-Hilbert spaces

Kuwait Journal of Science
Let A and B be two positive bounded linear operators acting on the complex Hilbert spaces H and K, respectively. In this paper, we study the (A⊗B)-numerical range WA⊗B(T⊗S) of the tensor product T⊗S for two bounded linear operators T and S on H and K ...
doaj   +1 more source

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

Molecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair, Philip König, Milena Mijović, Jessica Kalla, Anil Baskan, Loan Tran, Kristina Draganić, Pedro Morata Saldaña, Carlos Uziel Pérez Malla, Janette Pfneissl, Andreas Tiefenbacher, Julijan Kabiljo, Velina S. Atanasova, Lisa Wozelka‐Oltjan, Leonhard Müllauer, Michael Bergmann, Raheleh Sheibani‐Tezerji, Gerda Egger   +17 more
wiley   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Range dependent Hamiltonian algorithms for numerical QUBO formulation

Scientific Reports
With the advent and development of quantum computers, various quantum algorithms that can solve linear equations and eigenvalues faster than classical computers have been developed.
Hyunju Lee, Kyungtaek Jun
doaj   +1 more source

The international multi-system OSEs/OSSEs by the UN Ocean Decade Project SynObs and its early results

Frontiers in Marine Science
“Synergistic Observing Network for Ocean Prediction (SynObs)” was launched in 2022 as a project of the United Nations Decade of Ocean Science for Sustainable Development to evaluate the importance of ocean observation systems and co-design the future ...
Yosuke Fujii, Yosuke Fujii, Elisabeth Remy, Magdalena Alonso Balmaseda, Shoichiro Kido, Jennifer Waters, K. Andrew Peterson, Gregory C. Smith, Ichiro Ishikawa, Kamel Chikhar   +9 more
doaj   +1 more source

Eigenvalues in the boundary of the numerical range [PDF]

, 1970
Allan M. Sinclair
openalex   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source