Results 161 to 170 of about 456,012 (313)

Numerical Investigation on Critical Heat Flux for 5×5 Fuel Assemblies with a Wide Range of Working Conditions

, 2023
Xin Du, Ge Zhang, Lulu Lv, Ming Guo, Donghua Lu, Qianhua Su, Qifei Fang, Yan Ma   +7 more
openalex   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

The next frontier in healthcare: perspectives and discussion on building trust and societal acceptance of digital humans in the essential framework of impact biomechanics. [PDF]

Front Bioeng Biotechnol
Roth S.
europepmc   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Computer Model Based on an Asynchronous BLE 5.0 IMU Sensor Network for Biomechanical Applications. [PDF]

Sensors (Basel)
Mora-Sánchez JA, Sánchez-Fernández LP, González-Baldovinos DL, Zagaceta-Álvarez MT, Orantes-Jiménez SD.   +4 more
europepmc   +1 more source

On the normalized numerical range [PDF]

, 2017
Ilya M. Spitkovsky, Andrei-Florian Stoica   +1 more
openalex   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Relating estuarine turbidity maxima to tide and river conditions. [PDF]

Sci Rep
Grasso F, Bismuth E, Burchard H, Defontaine S, Kösters F, Lafite R, Reese L, Sottolichio A, van Kessel T, Vanlede J, van Maren DS, Walther R, Zorndt A.   +12 more
europepmc   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Analyses of Stress-State-Dependent Ductile Damage and Fracture Behavior of Zirconium. [PDF]

Materials (Basel)
Pan B, Zhu L, Wei Z, Tekkaya B, Stebner S, Münstermann S.   +5 more
europepmc   +1 more source