Results 61 to 70 of about 419,543 (296)
Journal of Advances in Modeling Earth Systems, 2020 The parametrization of orographic drag processes is a major source of circulation uncertainty in models. The COnstraining ORographic Drag Effects (COORDE) project makes a coordinated effort to narrow this uncertainty by bringing together the modeling ...
Annelize vanNiekerk +11 more
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Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
On numerical range of sp(2n, C)
Special Matrices, 2016 In this paper we studied the classical numerical range of matrices in sp(2n, C). We obtained some result on the relationship between the numerical range of a matrix in and that of its diagonal block, the singular values of its off-diagonal block A2.
Yan Wen, Tao Jicheng, Lu Zhao
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Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Some results on S-numerical range of operator matrices
Zanco Journal of Pure and Applied Sciences, 2020 A linear operator on a Hilbert space may be approximated with finite matrices by choosing an orthonormal basis of the Hilbert space. In this paper, we found an approximation of the S-numerical range of bounded and unbounded operator matrices by ...
Berivan Faris Azeez , Ahmed Muhammad
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Numerical Range and Quadratic Numerical Range for Damped Systems
, 2017 We prove new enclosures for the spectrum of non-selfadjoint operator matrices associated with second order linear differential equations $\ddot{z}(t) + D \dot{z} (t) + A_0 z(t) = 0$ in a Hilbert space. Our main tool is the quadratic numerical range for which we establish the spectral inclusion property under weak assumptions on the operators involved ...
Jacob, Birgit +3 more
openaire +2 more sources
Social context prevents heat hormetic effects against mutagens during fish development
FEBS Letters, EarlyView.This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere +5 more
wiley +1 more source
Autophagy in cancer and protein conformational disorders
FEBS Letters, EarlyView.Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
A stepwise emergence of evolution in the RNA world
FEBS Letters, EarlyView.How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley +1 more source
Norm Properties of $S$-Universal Operators
Communications in Advanced Mathematical Sciences, 2020 We investigate the norm properties of a generalized derivation on a norm ideal $\mathcal{J}$ in $\mathcal{B}(H)$, the algebra of bounded linear operators on a Hilbert space $H$.
Joshua Muholo, Job Bonyo
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