Results 71 to 80 of about 419,543 (296)

The carboxylate “gripper” of the substrate is critical for C‐4 stereo‐inversion by UDP‐glucuronic acid 4‐epimerase

FEBS Letters, EarlyView.
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg, Laura De Cnop, Bernd Nidetzky   +2 more
wiley   +1 more source

The upper numerical range of a quaternionic matrix is not a complex numerical range

Linear Algebra and its Applications, 1997
AbstractA recent result is that the quaternionic numerical range of a matrix with quaternion entries has a convex intersection with the upper half complex plane. This intersection is now shown to be generally not achievable as the upper half plane part of the complex numerical range of any complex matrix.
openaire   +2 more sources

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source

Exploring the ocean mesoscale at reduced computational cost with FESOM 2.5: efficient modeling strategies applied to the Southern Ocean [PDF]

Geoscientific Model Development
Modeled projections of climate change typically do not include a well-resolved ocean mesoscale due to the high computational cost of running high-resolution models for long time periods.
N. Beech, T. Rackow, T. Semmler, T. Jung, T. Jung   +4 more
doaj   +1 more source

Computing the q-Numerical Range of Differential Operators

Journal of Applied Mathematics, 2020
A linear operator on a Hilbert space may be approximated with finite matrices by choosing an orthonormal basis of thez Hilbert space. In this paper, we establish an approximation of the q-numerical range of bounded and unbounnded operator matrices by ...
Ahmed Muhammad, Faiza Abdullah Shareef
doaj   +1 more source

Numerical range and numerical radius for some operators

Linear Algebra and its Applications, 2010
AbstractThe numerical range and numerical radius of some model operators are investigated. Among other things, a complete description of the numerical range of square-zero operators on Hilbert spaces, including the skew-symmetric Volterra operator (V0f)(x)=∫-xxf(t)dt on the Lebesgue space L2(-1,1), is also given.
Karaev, M. T., Iskenderov, N. Sh.
openaire   +4 more sources

In vivo evidence for glycyl radical insertion into a catalytically inactive variant of pyruvate formate‐lyase

FEBS Letters, EarlyView.
Dimeric pyruvate formate‐lyase cleaves pyruvate using a radical‐based mechanism. G734 serves as a radical storage location, and the radical is transferred to the catalytic C419 residue. Mutation of the C418‐C419 pair causes loss of enzyme activity, but does not impede radical introduction onto G734. Therefore, cis‐ but not trans‐radical transfer occurs
Michelle Kammel, A. F. Volker Wagner, R. Gary Sawers   +2 more
wiley   +1 more source

P‐glycoprotein modulates the fluidity gradient of the plasma membrane of multidrug resistant CHO cells

FEBS Letters, EarlyView.
To explore the impact of the overexpression of the multidrug‐transporter P‐glycoprotein (ABCB1) on membrane fluidity, we compared the transversal gradient of mobility and microviscosity in plasma membranes of drug‐sensitive Chinese hamster ovary cells (AuxB1) and their multidrug‐resistant derivatives (B30) using the fluorescent n‐(9‐anthroyloxy) fatty ...
Roger Busche, John R. Riordan, Burkhard Tümmler   +2 more
wiley   +1 more source

On the joint numerical status and tensor products

International Journal of Mathematics and Mathematical Sciences, 1990
We prove a result on the joint numerical status of the bounded Hilbert space operators on the tensor products. The result seems to have nice applications in the multiparameter spectral theory.
Ram Verma, Lokenath Debnath
doaj   +1 more source

Evolutionary interplay between viruses and R‐loops

FEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi, Zita Képes, Zoltán Szabó, Eszter Csoma, Lóránt Székvölgyi   +4 more
wiley   +1 more source