Results 121 to 130 of about 3,114,017 (331)

Numerical Relativity Injection Infrastructure

open access: yes, 2017
This document describes the new Numerical Relativity (NR) injection infrastructure in the LIGO Algorithms Library (LAL), which henceforth allows for the usage of NR waveforms as a discrete waveform approximant in LAL.
Harry, Ian W.   +2 more
core  

Merger states and final states of black hole coalescences: a numerical-relativity-assisted effective-one-body approach

open access: yes, 2013
We study to what extent the effective-one-body description of the dynamical state of a nonspinning, coalescing binary black hole (considered either at merger, or after ringdown) agrees with numerical relativity results.
Damour, Thibault   +2 more
core   +1 more source

Modeling GW170817 based on numerical relativity and its implications [PDF]

open access: yes, 2017
Gravitational-wave observation together with a large number of electromagnetic observations shows that the source of the latest gravitational-wave event, GW170817, detected primarily by advanced LIGO, is the merger of a binary neutron star. We attempt to
M. Shibata   +6 more
semanticscholar   +1 more source

The IQ‐compete assay for measuring mitochondrial protein import efficiencies in living yeast cells

open access: yesFEBS Letters, EarlyView.
The efficiency of mitochondrial protein import depends on the properties of the newly synthesized precursor proteins. The Import and de‐Quenching Competition (IQ‐compete) assay is a novel method to monitor the import efficiency of different proteins by fluorescence in living yeast cells.
Yasmin Hoffman   +3 more
wiley   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Post-Newtonian Initial Data with Waves: Progress in Evolution

open access: yes, 2010
In Kelly et al. [Phys. Rev. D, 76:024008, 2007], we presented new binary black-hole initial data adapted to puncture evolutions in numerical relativity.
Campanelli, Manuela   +4 more
core   +1 more source

Numerical Hydrodynamics in General Relativity

open access: yesLiving Reviews in Relativity, 2000
The current status of numerical solutions for the equations of ideal general relativistic hydrodynamics is reviewed. Different formulations of the equations are presented, with special mention of conservative and hyperbolic formulations well-adapted to ...
Font José A.
doaj  

The zinc finger domains of PARP‐1 are selectively and potently inhibited by the Au(I)‐based drugs sodium aurothiomalate and aurothioglucose

open access: yesFEBS Letters, EarlyView.
PARP‐1 is a key enzyme in the DNA damage response, and its inhibition induces cancer cell death via synthetic lethality. Au(I)‐based drugs, such as aurothioglucose and sodium aurothiomalate, block PARP‐1's DNA‐dependent activity by targeting its zinc finger domains.
Uliana Bashtanova, Melinda Jane Duer
wiley   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

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