Results 81 to 90 of about 93,562 (275)

Computational Cosmology: from the Early Universe to the Large Scale Structure

Living Reviews in Relativity, 2001
In order to account for the observable Universe, any comprehensive theory or model of cosmology must draw from many disciplines of physics, including gauge theories of strong and weak interactions, the hydrodynamics and microphysics of baryonic matter ...
Anninos Peter
doaj  

Simulating Binary Neutron Stars with Hybrid Equation of States: Gravitational Waves, Electromagnetic Signatures and Challenges for Numerical Relativity

Particles, 2019
The gravitational wave and electromagnetic signatures connected to the merger of two neutron stars allow us to test the nature of matter at supranuclear densities.
Henrique Gieg, Tim Dietrich, Maximiliano Ujevic   +2 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Critical Phenomena in Gravitational Collapse

Living Reviews in Relativity, 1999
As first discovered by Choptuik, the black hole threshold in the space of initial data for general relativity shows both surprising structure and surprising simplicity.
Gundlach Carsten
doaj  

Performance-portable Numerical Relativity with AthenaK

The Astrophysical Journal Supplement Series
We present the numerical relativity module within AthenaK , an open-source performance-portable astrophysics code designed for exascale computing applications. This module employs the Z4c formulation to solve the Einstein equations.
Hengrui Zhu, Jacob Fields, Francesco Zappa, David Radice, James M. Stone, Alireza Rashti, William Cook, Sebastiano Bernuzzi, Boris Daszuta   +8 more
doaj   +1 more source

Newman-Penrose quantities as valuable tools in astrophysical relativity [PDF]

, 2004
In this talk I will briefly outline work in progress in two different contexts in astrophysical relativity, i.e. the study of rotating star spacetimes and the problem of reliably extracting gravitational wave templates in numerical relativity.
Bruni, Marco, Nerozzi, Andrea, White, Frances   +2 more
core   +2 more sources

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Rotating star initial data for a constrained scheme in numerical relativity

, 2006
A new numerical code for computing stationary axisymmetric rapidly rotating stars in general relativity is presented. The formulation is based on a fully constrained-evolution scheme for 3+1 numerical relativity using the Dirac gauge and maximal slicing.
, Bonazzola S, Bonazzola S, Choptuik M W, Gentle A P, Gourgoulhon E, Gourgoulhon E, Jérôme Novak, Lap-Ming Lin, Wald R M, York J W   +10 more
core   +2 more sources