Results 81 to 90 of about 137,188 (265)
Conservative numerical schemes for the Ostrovsky equation
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Takaharu Yaguchi +2 more
openaire +2 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
On the convergence of numerical schemes for the Boltzmann equation
We consider a time and spatial explicit discretisation scheme for the Boltzmannequation. We prove some Maxwellian bounds on the resulting approximated solution anddeduce its convergence using a new time-discrete averaging lemma. Résumé Nous considérons une discrétisation explicite en temps et espace de l’équation de ...
A. Vasseur, T. Horsin, S. Mischler
openaire +2 more sources
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
The implementation of algorithms for taking into account the stress-strain state in supercomputer modeling of vibroacoustic characteristics of technical objects in a domestic software package is presented.
M. B. Salin, I. A. Usacheva
doaj +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Volume-Preserving Schemes and Numerical Experiments
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Qin, M.-Z., Zhu, W.-J.
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Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
An explicit computational scheme is proposed for solving fractal time-dependent partial differential equations (PDEs). The scheme is a three-stage scheme constructed using the fractal Taylor series. The fractal time order of the scheme is three.
Yasir Nawaz +4 more
doaj +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source

