Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
A tension spline fitted numerical scheme for singularly perturbed reaction-diffusion problem with negative shift. [PDF]
BMC Res Notes, 2023 Ejere AH +3 more
europepmc +1 more source
An implicit Keller Box numerical scheme for the solution of fractional subdiffusion equations
, 2019 In this work, we present a new implicit numerical scheme for fractional subdiffusion equations. In this approach we use the Keller Box method [1] to spatially discretise the fractional subdiffusion equation and we use a modified L1 scheme (ML1), similar ...
Osman, S. A, Langlands, T. A. M.
core +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
On the construction of boundary preserving numerical schemes [PDF]
Monte Carlo Methods and Applications, 2016 Abstract Our aim in this note is to extend the semi-discrete technique by combine it with the split step method. We apply our new method to the Ait-Sahalia model and propose an explicit and positivity preserving numerical scheme.
openaire +3 more sources
A new explicit numerical scheme for enhancement of heat transfer in Sakiadis flow of micro polar fluid using electric field. [PDF]
Heliyon, 2023 Nawaz Y +4 more
europepmc +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
An efficient numerical scheme for fractional host–parasite hyperparasite interaction model
Applied Mathematics in Science and EngineeringIn this paper, we analyse the unique characteristics of hyperparasites and discharge incidents in the initial stage of parasite populations. If hyperparasites are effectively developed in a population, they can play a crucial role in controlling host ...
Parveen Kumar +3 more
doaj +1 more source
An Efficient Numerical Scheme for Solving a Fractional-Order System of Delay Differential Equations. [PDF]
Int J Appl Comput Math, 2022 Kumar M.
europepmc +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source