Results 141 to 150 of about 225,512 (313)
Phosphoinositides and inositol phosphates as molecular glues
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Efficient parallel computing with a compact finite difference scheme
This paper proposes an efficient parallel computing approach based on a high-order accurate compact finite difference scheme in conjunction with a conventional domain decomposition method and MPI libraries.
Kim, J.W., Sandberg, R.D.
core +1 more source
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
This study explores the spread of malware within a digital framework by introducing a unique fractional-order model that employs the Atangana–Baleanu–Caputo (ABC) derivative.
Tharmalingam Gunasekar +4 more
doaj +1 more source
A numerical scheme for the ground state of rotating spin-1 Bose-Einstein condensates. [PDF]
Sriburadet S +4 more
europepmc +1 more source
α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino +2 more
wiley +1 more source
A numerical scheme using multi-shockpeakons to compute solutions of the Degasperis-Procesi equation
We consider a numerical scheme for entropy weak solutions of the DP (Degasperis-Procesi) equation $u_t - u_{xxt} + 4uu_x = 3u_{x}u_{xx}+ uu_{xxx}$. Multi-shockpeakons, functions of the form $$ u(x,t) =sum_{i=1}^n(m_i(t) -hbox{sign}(x-x_i(t))s_i(t ...
Hakon A. Hoel
doaj
Accurate numerical scheme for singularly perturbed parabolic delay differential equation. [PDF]
Woldaregay MM, Duressa GF.
europepmc +1 more source
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Monte Carlo Simulation with Asymptotic Method (Published in "Journal of Japan Statistical Society", Vol.35-2, 171-203, 2005. ) [PDF]
We shall propose a new computational scheme with the asymptotic method to achieve variance reduction of Monte Carlo simulation for numerical analysis especially in finance. We not only provide general scheme of our method, but also show its effectiveness
Nakahiro Yoshida, Akihiko Takahashi
core

