Results 121 to 130 of about 3,128,332 (289)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
A uniformly convergent numerical scheme for solving singularly perturbed differential equations with large spatial delay. [PDF]
SN Appl Sci, 2022 Ejere AH +3 more
europepmc +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
An adaptive gridding technique for conservation laws on complex domains [PDF]
, 1997 Obtaining accurate solutions to flows that involve discontinuous features still re- mains one of the most difficult tasks in computational fluid dynamics today.
Boden, E. P.
core +1 more source
AlgorithmsThis study explores the spread of malware within a digital framework by introducing a unique fractional-order model that employs the Atangana–Baleanu–Caputo (ABC) derivative.
Tharmalingam Gunasekar +4 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
A numerical scheme for the ground state of rotating spin-1 Bose-Einstein condensates. [PDF]
Sci Rep, 2021 Sriburadet S +4 more
europepmc +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
, 2016 In this paper, we consider the Euler method for backward stochastic Volterra integral equations. First, we approximate the original equation by a family of backward stochastic equations (BSDEs, for short). Then we solve the BSDEs by the Euler method.
openaire +2 more sources
Numerical schemes for the solution of the telegrapher equation
Numerical AlgorithmsAbstract The present work deals with the numerical resolution of the telegrapher equation. We present various numerical explicit and implicit schemes for problems defined in one-dimensional domains. In this case, we consider, on one hand, Dirichlet boundary value conditions and in the other hand, the mixed ones.
Pierre Spitéri, Frédéric Messine
openaire +1 more source