Results 131 to 140 of about 3,128,332 (289)
A numerical scheme using multi-shockpeakons to compute solutions of the Degasperis-Procesi equation
We consider a numerical scheme for entropy weak solutions of the DP (Degasperis-Procesi) equation $u_t - u_{xxt} + 4uu_x = 3u_{x}u_{xx}+ uu_{xxx}$. Multi-shockpeakons, functions of the form $$ u(x,t) =sum_{i=1}^n(m_i(t) -hbox{sign}(x-x_i(t))s_i(t ...
Hakon A. Hoel
doaj
A Two-Step High-Order Compact Corrected WENO Scheme
In this study, we introduce a novel 2-step compact scheme-based high-order correction method for computational fluid dynamics (CFD). Unlike traditional single-formula-based schemes, our proposed approach refines flux function values by leveraging results
Yong Yang +3 more
doaj +1 more source
Accurate numerical scheme for singularly perturbed parabolic delay differential equation. [PDF]
Woldaregay MM, Duressa GF.
europepmc +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Production and dispersion of free radicals from transient cavitation Bubbles: An integrated numerical scheme and applications. [PDF]
Peng K, Qin FGF, Jiang R, Qu W, Wang Q.
europepmc +1 more source
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
A high order compact scheme for hypersonic aerothermodynamics [PDF]
A novel high order compact scheme for solving the compressible Navier-Stokes equations has been developed. The scheme is an extension of a method originally proposed for solving the Euler equations, and combines several techniques for the solution of ...
Emerson, David +2 more
core +1 more source
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source

