Results 71 to 80 of about 244,921 (262)
Impulsive Switching Epidemic Model with Benign Worm Defense and Quarantine Strategy
Complexity, 2020 The issue on how to effectively control Internet malicious worms has been drawn significant attention owing to enormous threats to the Internet. Due to the rapid spreading of malicious worms, it is necessary to explore the integrated measures to ...
Jiying Lai +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
On a Stochastic SEIS Model with Treatment Rate of Latent Population
Abstract and Applied Analysis, 2014 The asymptotic dynamics of a stochastic SEIS epidemic model with treatment rate of latent population is investigated. First, we show that the system provides a unique positive global solution starting from the positive initial value.
Shujing Gao +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Geometrical fingerprints of shear transformation zones in network glasses
Communications MaterialsOur understanding of the fracture behavior of oxide glasses is rudimentary at best, since the mechanical behavior is hidden behind complex disordered network structures.
Franz Bamer +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong +3 more
wiley +1 more source
New Second-Order Finite Difference Scheme for the Problem of Contaminant in Groundwater Flow
Journal of Applied Mathematics, 2012 We develop a new efficient second-order finite difference scheme for two-dimensional problem of contaminant in groundwater flow. Theoretical analysis shows that the scheme is second-order convergence in the L2 norm and is unconditionally stable ...
Quanyong Zhu +3 more
doaj +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
FEBS Open Bio, EarlyView.Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
FEBS Open Bio, EarlyView.PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source