Results 11 to 20 of about 3,002,634 (211)
COMPARATION ON SEVERAL SMOOTHING METHODS IN NONPARAMETRIC REGRESSION [PDF]
There are three nonparametric regression methods covered in this section. These are Moving Average Filtering-Based Smoothing, Local Regression Smoothing, and Kernel Smoothing Methods.
Isnanto, R.Rizal, Rizal Isnanto, R
core +1 more source
Scattered data fitting on surfaces using projected Powell-Sabin splines [PDF]
We present C1 methods for either interpolating data or for fitting scattered data associated with a smooth function on a two-dimensional smooth manifold Ω embedded into R3. The methods are based on a local bivariate Powell-Sabin interpolation scheme, and
Schumaker, L.L., Davydov, Oleg
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P-spline anova-type interaction models for spatio-temporal smoothing [PDF]
In recent years, spatial and spatio-temporal modelling have become an important area of research in many fields (epidemiology, environmental studies, disease mapping, ...).
Lee, Dae-Jin +1 more
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Smoothing with Curvature Constraints based on Boosting Techniques [PDF]
In many applications it is known that the underlying smooth function is constrained to have a specific form. In the present paper, we propose an estimation method based on the regression spline approach, which allows to include concavity or convexity ...
Gerhard Tutz +3 more
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Bayesian curve estimation by model averaging [PDF]
A bayesian approach is used to estimate a nonparametric regression model. The main features of the procedure are, first, the functional form of the curve is approximated by a mixture of local polynomials by Bayesian Model Averaging (BMA); second, the ...
Peña, Daniel, Redondas, María Dolores
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The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Efficient algorithms for robust generalized cross-validation spline smoothing [PDF]
Generalized cross-validation (GCV) is a widely used parameter selection criterion for spline smoothing, but it can give poor results if the sample size n is not sufficiently large.
Anderssen, R.S. +5 more
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Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source

