Results 11 to 20 of about 5,219 (218)

Estimation of a regression spline sample selection model [PDF]

open access: yes, 2013
It is often the case that an outcome of interest is observed for a restricted non-randomly selected sample of the population. In such a situation, standard statistical analysis yields biased results.
Marra, Giampiero   +5 more
core   +1 more source

Discrete Differential Operators for Computer Graphics [PDF]

open access: yes, 2004
This thesis presents a family of discrete differential operators. Since these operators are derived taking into account the continuous notions of differential geometry, they possess many similar properties.
Meyer, Mark
core   +1 more source

Space-Varying Coefficient Models for Brain Imaging [PDF]

open access: yes, 2005
The methodological development and the application in this paper originate from diffusion tensor imaging (DTI), a powerful nuclear magnetic resonance technique enabling diagnosis and monitoring of several diseases as well as reconstruction of neural ...
Marx, Brian D.   +3 more
core   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

A jump-preserving curve fitting procedure based on local piecewise-linear kernel estimation

open access: yes, 2003
It is known that the fitted regression function based on conventional local smoothing pro-cedures is not statistically consistent at jump positions of the true regression function.
Peihua Qiu
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

“Looking for nothing" bayes linear methods for solving equations [PDF]

open access: yes, 1993
Here I will describe and implement Bayes linear methods for finding zeros of deterministic functions. We assume that the zero is known to be unique. Initially, the value of the function is modelled simply as the product of two independent factors, the ...
Smith, J.A, Smith, James A.
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

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