Results 181 to 190 of about 2,129,625 (339)
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Exploring potential hidden aspects of quantum field theory through numerical solution of the Klein-Gordon equation using the Yee algorithm. [PDF]
Honarbakhsh B.
europepmc +1 more source
Modelling the spread of covid-19 in the capital of Brazil using numerical solution and cellular automata. [PDF]
Cavalcante ALB +4 more
europepmc +1 more source
Certification of Algorithm 30: Numerical solution of the polynomial equation [PDF]
Kalman J. Cohen
openalex +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Stabilisation of the Landau-Lifshitz-Gilbert equation for numerical solution via standard methods. [PDF]
Botha AE.
europepmc +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source

