Results 201 to 210 of about 2,129,625 (339)

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

A local meshless method for the numerical solution of multi-term time-fractional generalized Oldroyd-B fluid model. [PDF]

Heliyon
Aljawi S, Kamran, Aloqaily A, Mlaiki N.
europepmc   +1 more source

A numeric solution for metric-affine gravity and Einstein's gravitational theory with Proca matter

, 1999
Marc Toussaint
openalex   +2 more sources

Direct construction of optimized stellarator shapes. Part 2. Numerical quasisymmetric solutions [PDF]

, 2019
Matt Landreman, Wrick Sengupta, Gabriel G. Plunk   +2 more
openalex   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Numerical solution and experimental investigation for hydro-acoustic analysis and noise reduction assessment of ship ducted propeller. [PDF]

Heliyon
Alizadeh V, Abbaspour M, Mohseni Arasteh A, Lari K, Torabi Azad M.   +4 more
europepmc   +1 more source

Numerical procedure for planetary wave solution

, 1993
Woo Kap Choi, Donald J. Wuebbles
openalex   +2 more sources

A family of numerical methods for the numerical solution of Blasius' equation [PDF]

, 1986
Twizell, E H
core  

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Research on the prediction model of energy separation effect of vortex tube based on trajectory deflection characteristics and its numerical solution method. [PDF]

Heliyon
Liu S, Cao S, Han Z, Li S, Li Q, Zhang J, Xu H.   +6 more
europepmc   +1 more source