Results 101 to 110 of about 191,474 (264)
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
دراسة الاستقراریة العددیة لطرائق رانج-کوتا التجمیعیة الصریحة-الضمنیة
Al-Rafidain Journal of Computer Sciences and Mathematics, 2010 Thair Y. Thanoon, Younis Abd Hussain
doaj +1 more source
Demonstratio MathematicaThis paper presents the development and analysis of a multi-step multi-derivative numerical approach designed to solve fourth-order ordinary differential equations with constant coefficients.
Ibrahimov Vagif +3 more
doaj +1 more source
SUPG-stabilized stabilization-free VEM: a numerical investigation
Mathematics in Engineering<abstract><p>We numerically investigate the possibility of defining Stabilization-Free Virtual Element discretizations–i.e., Virtual Element Method discretizations without an additional non-polynomial non-operator-preserving stabilization term–of advection-diffusion problems in the advection-dominated regime, considering a Streamline Upwind
Borio, Andrea +2 more
openaire +5 more sources
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
طرائق الفروقات المنتهیة لمعادلة Klein-Gordon
Al-Rafidain Journal of Computer Sciences and Mathematics, 2008 Saad A. Manaa, Laya Y. Hawell
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Sensitivity Analysis and a New Inverse Algorithm of Elastic Parameters for Gravity Dam
工程科学与技术, 2006 :The research of finding optimal observation place for inversing concrete gravity dam parameters was studied firstly through analytical sensitivity analysis theory, the conclusion indicated that the displacement of dam crest is the most suitable data for
doaj
FEBS Letters, EarlyView.Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley +1 more source
Numerical stability of spline-based Gabor-like systems. [PDF]
Proc Eur Signal Process Conf EUSIPCO, 2018 Onchis DM, Zappalà S, Real P, Istin C.
europepmc +1 more source