Results 61 to 70 of about 17,808 (248)

The Nuclear Receptor Testicular Receptor 4 Orchestrates Cytoskeletal Organization in a G Protein Subunit Alpha 12/Rho‐Associated Protein Kinase–Dependent Manner to Promote Myofibroblast Differentiation and Tissue Fibrosis in Systemic Sclerosis

Arthritis &Rheumatology, EarlyView.
Objective Members of the superfamily of nuclear receptors have been implicated in inflammatory processes and pathologic tissue remodeling and have emerged as attractive targets for pharmaceutical intervention. However, the role of testicular receptor 4 (TR4; or Nr2c2) in fibroblast activation and rheumatologic diseases has not yet been investigated ...
Yun Zhang, Lichong Shen, Junhui Zheng, Gisela Baur, Dilidaer Yasen, Honglin Zhu, Yi‐Nan Li, Xianyi Meng, Thuong Trinh‐Minh, Tim Filla, Debomita Chakraborty, Andrea‐Hermina Györfi, Christina Bergmann, Adam Reich, Alexander Kreuter, Georg Schett, Jörg H. W. Distler   +16 more
wiley   +1 more source

Charlotte Pommer: Resistance fighter and female pioneer of German anatomy

Anatomical Sciences Education, EarlyView.
Abstract This article examines the biography and unique case of Charlotte Pommer (1914–2004), the only anatomist documented to have left the field during the Nazi period after encountering the regime's victims on the dissection table. While she is known for her resistance activities, newly presented documentation reveals her role as the provisional ...
Tim S. Goldmann
wiley   +1 more source

Sala Maestros Cantores - Nuremberg (Alemania)

Informes de la Construccion, 1971
El acceso a la Sala de Conciertos se realiza a través del vestíbulo de entrada, zona de guardarropas y gran «foyer» —en comunicación visual con un amplio patio tratado paisajísticamente, lográndose una incorporación del ambiente exterior, al del interior—
H. Loebermann
doaj   +1 more source

Combined effect of increasing the post‐reformer temperature and adding red mud as a secondary catalyst in the thermocatalytic reforming of digestate

Biofuels, Bioproducts and Biorefining, EarlyView.
Abstract This work studies the combined effect of increasing the post‐reformer temperature and introducing red mud as a support catalyst in the thermocatalytic reforming (TCR®) of digestate. The TCR® method, developed by the Fraunhofer Institute for Environmental, Safety and Energy Technology UMSICHT (abbreviated as Fraunhofer UMSICHT), is an extension
Hillary Onyishi, Johannes Neidel, Robert Daschner, Andreas Apfelbacher, Andreas Hornung   +4 more
wiley   +1 more source

Feasibility and diagnostic accuracy of ischemic stroke territory recognition based on two-dimensional projections of three-dimensional diffusion MRI data

Frontiers in Neurology, 2015
This study was conducted to assess the feasibility and diagnostic accuracy of brain artery territory recognition based on geoprojected two-dimensional maps of diffusion MRI data in stroke patients.
Jana Katharina Wrosch, Bastian eVolbers, Bastian eVolbers, Philipp eGölitz, Daniel F. Gilbert, Stefan eSchwab, Arnd eDörfler, Johannes eKornhuber, Teja Wolfgang Groemer, Teja Wolfgang Groemer   +9 more
doaj   +1 more source

Comprehensive Peptide Profiling Reveals the Influence of Streptococcus Thermophilus, Lactobacillus Delbrueckii Subsp. bulgaricus, and Endogenous Milk Proteases on the Hydrolysis of Milk Proteins During Early‐Stage Lactic Acid Fermentation

ChemFoodChem, EarlyView.
Untargeted peptide profiling investigates how S. thermophilus, Lb. bulgaricus, and endogenous milk enzymes impact proteolysis during early‐stage milk fermentation. ≥ 3000 identified peptides show the strongest influence of LB on the peptide profile and number of bioactive peptides. Shorter peptides are mostly formed by LB and hydrolyzed by ST.
Eva Beck, Lena Riedinger, Sevim Dalabasmaz, Joachim Stützer, Luisa Bähr, Rohtraud Pichner, Monika Pischetsrieder   +6 more
wiley   +1 more source

A Selectfluor‐based Polonovski Rearrangement Leading to Novel Entities for Synthetic and Medicinal Applications

Chemistry – A European Journal, EarlyView.
Starting from carboxylic acids and Selectfluor‐derivatives, functionalized diazabicyclooctanes can be obtained via a novel Polonovski‐type rearrangement proceeding under mild reaction conditions. Besides their use in organic synthesis the unique structure and reactivity of the rearrangement products enables applications in medicinal chemistry ...
Jakob Kuhn, Susanne Gradl, Vanessa Osterloh, Peter Gmeiner, Harald Hübner, Markus R. Heinrich   +5 more
wiley   +1 more source

Multimodal Fluorescent MOF@BODIPY Platform: Bridging Sensing and Mechanistic Insight

Chemistry – A European Journal, EarlyView.
ABSTRACT Hybrid metal–organic frameworks (MOFs) that integrate organic chromophores constitute powerful platforms for optical sensing by combining structural order with tunable photophysics. Incorporating photoresponsive chromophores into MOFs enables sensitive probing of guest–framework interactions through well‐defined luminescent signatures. Herein,
Alejandro Cortés‐Villena, Paula Rodrigo‐Martínez, José A. Sáez, Pablo Gaviña, Emilio Pardo, Raquel E. Galian, Sergio Armenta, Héctor Martínez‐Pérez‐Cejuela, José Manuel Herrero‐Martínez   +8 more
wiley   +1 more source

Effects of Trimethoprim on Three Previously Proposed Putative Biomarkers for OCT2/MATE‐Mediated Renal Drug‐Drug Interactions in Healthy Volunteers

Clinical Pharmacology &Therapeutics, EarlyView.
Regulatory agencies request the assessment of the potential of new drugs to cause transporter‐mediated drug‐drug interactions (DDI). This assessment can be improved by integrating endogenous biomarkers during drug development. Regarding the renal excretion of drugs such as metformin, the organic cation transporter (OCT) 2 and multidrug and toxin ...
Jana Picurová, Fabian Müller, Daniel Auge, Jörg König, Martin F. Fromm, Arne Gessner   +5 more
wiley   +1 more source

Evaluation of Capacitive Markers Fabricated by 3D Printing, Laser Cutting and Prototyping

Inventions, 2018
With Tangible User Interfaces, the computer user is able to interact in a fundamentally different and more intuitive way than with usual 2D displays. By grasping real physical objects, information can also be conveyed haptically, i.e., the user not only ...
Julian Kreimeier, Thomas Bielmeier, Timo Götzelmann   +2 more
doaj   +1 more source