Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Academic Nurse Educators' Experiences and Perceptions of Supporting Adult Nursing Students in Clinical Placements in Nursing Homes: An Interpretative Phenomenological Analysis. [PDF]
Int J Older People NursCooke J +3 more
europepmc +1 more source
Aging and Cancer, EarlyView.This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel +4 more
wiley +1 more source
Trends in Interventional Pain Management Procedures Performed by Nurse Anesthetists: A Retrospective Cross-sectional Study. [PDF]
AnesthesiologyHyman MJ, Modi PK, Kremer MJ, Sun EC.
europepmc +1 more source
Hospital Readmission After Traumatic Brain Injury Hospitalization in Community‐Dwelling Older Adults
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To examine the risk of hospital readmission after an index hospitalization for TBI in older adults. Methods Using data from the Atherosclerosis Risk in Communities (ARIC) study, we used propensity score matching of individuals with an index TBI‐related hospitalization to individuals with (1) non‐TBI hospitalizations (primary analysis)
Rachel Thomas +7 more
wiley +1 more source
Nursing Workload in Systemic Anti-Cancer Therapy Day Units: A Scoping Review and Gap Analysis. [PDF]
Nurs Health SciBao Z +5 more
europepmc +1 more source
Nursing Science, Nursing Theory: Nurse Atheists, Nurse Agnostics, Nurse Theists [PDF]
Nursing Science Quarterly, 2018 openaire +2 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source
Nurses' Adherence to Double-Checking: A Systematic Review of Influencing Factors, Improvement Strategies, and Their Effectiveness. [PDF]
Int Nurs RevZhao J, Liu H, Shan A, Peng Y, Or CKL.
europepmc +1 more source