Results 71 to 80 of about 124,584 (308)

Neuronal FGF13 Inhibits Mitochondria‐Derived Damage Signals to Prevent Neuroinflammation and Neurodegeneration in a Mouse Model of Parkinson's Disease

Advanced Science, EarlyView.
This study elucidates a novel role of FGF13 in manipulating neuronal fate via mitochondrial transfer. FGF13 is identified as a mitochondria‐stabilizing protein by interacting with mitochondrial proteins. Under stress, the decrease of neuronal FGF13 fails to retain mitochondria within the cytoplasm, leading to the release of damaged mitochondria to ...
Nanshan Song, Xiangxu Wang, Luqing Ha, Lamei Hu, Shuyuan Mei, Yue Liang, Yujie Zhao, Xingyin Yang, Qingyu Zhang, Yuanzhang Zhou, Jianhua Ding, Yan Liu, Qigang Zhou, Feng Han, Gang Hu, Ming Lu   +15 more
wiley   +1 more source

Targeting Hyperglycemic Bone Pre‐Metastatic Niche for Breast Cancer Bone Metastasis Therapy

Advanced Science, EarlyView.
This study reveals that breast cancer creates a hyperglycemic pre‐metastatic niche in bone prior to colonization and amplifies glucose metabolism post‐metastasis. To target this mechanism, a biomimetic enzyme‐engineered nanoplatform that disrupts tumor glycolytic pathways, proposing a therapeutic strategy to inhibit breast cancer bone metastasis by ...
Jianxin Ye, Peng Hu, Rui Zhang, Lei Zhou, Zonghua Luo, Yanan Chen, Shengzhe Ruan, Mengyi Zhu, Huaze Ding, Yike Qian, Yan Xing, Tong Meng, Changping Wang, Dianwen Song   +13 more
wiley   +1 more source

Using Mobile Health to Support the Chronic Care Model: Developing an Institutional Initiative

International Journal of Telemedicine and Applications, 2012
Background. Self-management support and team-based care are essential elements of the Chronic Care Model but are often limited by staff availability and reimbursement.
Shantanu Nundy, Jonathan J. Dick, Anna P. Goddu, Patrick Hogan, Chen-Yuan E. Lu, Marla C. Solomon, Arnell Bussie, Marshall H. Chin, Monica E. Peek   +8 more
doaj   +1 more source

Development of a Self‐Management Theory‐Guided Discharge Intervention for Parents of Hospitalized Children [PDF]

, 2017
Background Parents of hospitalized children, especially parents of children with complex and chronic health conditions, report not being adequately prepared for self‐management of their child\u27s care at home after discharge.
Gralton, Karen, Johnson, Norah L., Kaul, Molly, Klingbeil, Carol, Lerret, Stacee M., Malin, Shelly, Sawin, Kathleen, Schiffman, Rachel, Thompson, Jamie J., Weiss, Marianne, Zimmanck, Kim   +10 more
core   +1 more source

Boosting the Efficiency and Mechanical Stability of Organic Solar Cells Through a Polymer Acceptor by Reducing the Elastic Modulus

Advanced Energy Materials, EarlyView.
Herein, PYSe2F‐T is first applied to simultaneously improve the performance and mechanical stability of organic solar cells compared with mPh4F‐TS as the counterpart. Meanwhile, a detailed crack density analysis is first employed to evaluate the relationship between mechanical stability and elastic modulus of active layers, which can be reduced by the ...
Yan Wang, Han Yu, Dan Zhao, Wei Liu, Baoze Liu, Xin Wu, Danpeng Gao, Dong Zhang, Shoufeng Zhang, Xianglang Sun, Chunlei Zhang, Chaoyue Zhao, Yuchen Fu, Wei Song, Shaokuan Gong, Yuang Fu, Chung Hang Kwok, Ziyi Ge, Xinhui Lu, Xihan Chen, Shuang Xiao, Wai‐Yeung Wong, Yu Chai, He Yan, Zonglong Zhu   +24 more
wiley   +1 more source

Genomics Review of Selective RET Inhibitors Sensitivity in Thyroid Cancer Clinical Trials

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT RET gene is a driver of thyroid cancer (TC) tumorigenesis. The incidence of TC has increased worldwide in the last few decades, both in medullary and follicular‐derived subtypes. Several drugs, including multikinase and selective inhibitors, have been explored.
Sara Gil‐Bernabé, Lucía García‐DeLaFuente, Alejandro García‐Álvarez, Ginesa García‐Rostán, Jaume Capdevila, Jorge Hernando   +5 more
wiley   +1 more source

Correlation between Nurse /Manager Professional Collaborative Behaviors and Nurses’ Job Satisfaction

نشریه پرستاری ایران, 2018
Background & Aim: Professional collaboration play an important role in workplace’ health in healthcare organizations. Improving this collaboration may effect on nursing job satisfaction. This study aimed to determine the correlation between nurse/manager
N Pasyar, M Rambod, S Gholamzadeh, F Sharif   +3 more
doaj  

Factors associated with the job satisfaction of certified nurses and nurse specialists in cancer care in Japan: Analysis based on the Basic Plan to Promote Cancer Control Programs.

PLoS ONE, 2020
BACKGROUND:As the Japanese population ages, the number of cancer patients will likely increase. Therefore, qualified cancer health care providers should be recruited and retained.
Masaki Kitajima, Chiharu Miyata, Keiko Tamura, Ayae Kinoshita, Hidenori Arai   +4 more
doaj   +1 more source

Perceptions of Professional Practice and Work Environment of New Graduates in a Nurse Residency Program [PDF]

, 2011
New nurses continue to face challenging work environments and high expectations for professional competence as they enter practice. Nurse residency programs are gaining prominence as a mechanism to ease new graduates’ transition to practice.
Bratt, Marilyn Meyer, Felzer, Holly M.
core   +1 more source

A scoping review of non‐binary research in “Australian” social sciences: Community, solidarity, resilience and resisting marginalisation

Australian Journal of Social Issues, EarlyView.
Abstract Non‐binary and genderqueer identities are increasingly discussed in public discourse and academia, but there remains a dearth of academic literature centred on non‐binary people's lives and experiences. When non‐binary people are included in research, it is frequently as an additive to explorations of trans identities and subsumed under the ...
Lucy Nicholas, Sal Clark, Chloe Falzon
wiley   +1 more source