Results 91 to 100 of about 9,896,927 (296)

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Influence of Leadership, Work Discipline, and Work Motivation on Nurse Performance in the Inpatient Ward of TK IV 02.07.04 Hospital Bandar Lampung

open access: yesDanadyaksa
Nurse performance is a critical factor in determining the quality of healthcare services in hospitals; however, issues related to leadership, work discipline, and work motivation are still frequently identified as factors that potentially affect nurse ...
Rio Yoga Erlambang   +5 more
doaj  

THE REFLECTIVE SUPERVISION MODEL: AN EFFORT TO INCREASE NURSE JOB SATISFACTION

open access: yesBelitung Nursing Journal, 2017
Background: Job satisfaction influences the quality of health services in hospitals. However, low job satisfaction of nurses exists in the literature and influenced by various factors, including supervision.
Santoso, Rita Kartika Sari, Anggorowati
doaj  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Moderating effect of inclusive leadership on nurse conflicts and nursing team work atmosphere

open access: yesHuli yanjiu
ObjectiveTo explore the relationship between nurse conflict,service atmosphere,and safety atmosphere,as well as the moderating effect of inclusive leadership.MethodsA total of 1 509 nurses from 5 hospitals in Yangquan city were selected as the research ...
LIU Liqin   +3 more
doaj  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Assessment of The Nurse Interns' Medication Administration Safety Performance

open access: yesEvidence-Based Nursing Research
Contents: Medication administration is an integral part of delivering quality nursing care. The nurse intern should follow the specific guidelines to enhance their medication administration safety.
Asmaa S. Saber, Harisa M. A. Elshemy
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

A history of nurse education and the clinical nurse educator

open access: yes, 2019
This chapter discusses the potential roles which will be engendered by the new Nursing and Midwifery Council standards and framework for nurse education. Woven throughout the account will be the clinical nurse educator roles which have fulfilled the need
Bill Whitehead, Whitehead, Bill
core   +1 more source

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