Results 101 to 110 of about 700,451 (244)

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

1946 Annual Report : Visiting Nurse Association of Omaha

open access: yes, 1947
CONTENTS: Glimpses Into the Past : Fifty years ago The Visiting Nurse Association ot Omaha ceased being one woman’s dream and became instead a force for good that has prospered ...
Visiting Nurse Association of Omaha
core  

The Relationship Between Nurses' Happiness and The Transformational Leadership Style of Nurse Managers

open access: yesSağlık ve Hemşirelik Yönetimi Dergisi
Aim: The aim of this study is to determine the relationship between the happiness of nurses and the transformational leadership of nurse managers. Method: This study was conducted a descriptive and correlational design.
Burcu Kıy, Gülnur Akkaya
doaj   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

Nurse manager Psychological Capital as a predictor of perceived nurse manager ability to foster a healthy work environment [PDF]

open access: yes, 2018
2018 Spring.Includes bibliographical references.The purpose of this study was to examine the relationship between a nurse manager's level of Positive Psychological Capital (PsyCap) and his or her ability to foster a healthy work environment as perceived ...
Feller, Richard W., committee member   +4 more
core  

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

open access: yesMolecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler   +3 more
wiley   +1 more source

Nurses' Metaphorical Perceptions About Their Managers: A mixed-method research

open access: yesAsia Pacific Journal of Health Management
Background: Research in literature have examined the leadership styles of nurse managers. However, no qualitative study based on metaphors could be found to determine the perceptions of nurses regarding their managers in depth and without limitations ...
Serap Altuntaş   +2 more
doaj   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Development and testing of the Nurse Manager EBP Competency Scale [PDF]

open access: yes, 2017
Background: Nurse managers are ideally situated within an organization to influence implementation and use of evidence-based practices (EBP) (Birken, Lee, & Weiner, 2012; Stetler, Ritchie, Rycroft-Malone, & Charns, 2014).
Titler, Marita G., Shuman, Clayton J.
core   +1 more source

Home - About - Disclaimer - Privacy