Results 121 to 130 of about 662,758 (290)

Integrated Single‐Cell and TCR Profiling Reveals Protection‐Associated CD8+ T Cell Subsets Linked to Viral Control in PRRSV

open access: yesAdvanced Science, EarlyView.
PRRSV vaccine‐mediated protection is associated with clonally expanded cytotoxic CD8+ T cell subsets driven by viral structural proteins and supported by innate TLR4/TLR8 signaling and CD4+ T cell help, whereas non‐protective responses are characterized by dysfunctional exhausted‐like CD8+ T cells linked to poor viral control.
Can Kong   +14 more
wiley   +1 more source

CERTIFICATION OF CLINICAL NURSE SPECIALIST [PDF]

open access: yes, 2014
definition of the title Clinical Nurse Specialist, (Business and Professions Code, Division 2 ...
Louise R. Bailey, Executive Officer
core  

Trafficking Deficiency of TMEM175 Variants in Parkinson's Disease Pathogenesis and the Prospects of Precision Medicine

open access: yesAdvanced Science, EarlyView.
This study identifies that the PD‐associated TMEM175‐L156P variant disrupts lysosomal ion channel trafficking by causing aberrant endoplasmic reticulum retention. A “chaperone–agonist” bifunctional small molecule restores TMEM175‐L156P lysosomal localization and channel function, thereby alleviating PD‐relevant cellular phenotypes and highlighting a ...
Ting Luo   +17 more
wiley   +1 more source

Board of Nurse Examiners for the State of Texas: Rules and Regulations Relating to Professional Nurse Education, Licensure and Practice [PDF]

open access: yes, 1995
Handbook issued by the Board of Nurse Examiners including the text of laws related to the education, licensing, and practice of Texas ...
Texas. Board of Nurse Examiners.
core  

Pasta, a Versatile Transcriptomic Clock, Maps the Chemical and Genetic Determinants of Aging and Rejuvenation

open access: yesAdvanced Science, EarlyView.
Pasta is a transcriptomic aging clock built on an age‐shift learning framework and trained on 17 000 samples across 21 datasets. It accurately predicts relative biological age across tissues, platforms, and species, captures stemness‐to‐senescence transitions, and identifies age‐modulatory perturbations.
Jérôme Salignon   +6 more
wiley   +1 more source

The Agile Clinical Nurse Specialist: Navigating the Challenges of the COVID-19 Pandemic. [PDF]

open access: yesClin Nurse Spec, 2022
Mamais F   +6 more
europepmc   +1 more source

Gαi1/3 Are Essential for BMP2‐Induced Osteogenesis by Bridging BMP Receptors to the Gab1 Signaling Complex

open access: yesAdvanced Science, EarlyView.
The Gαi1/3 protein is a crucial connecting protein closely related to the signal transduction process of bone formation‐related cytokines such as BMP2. Gαi1/3 mediates downstream signaling pathways such as Smads and MAPK by binding to adaptor proteins like Gab1, thereby promoting the osteogenic effect of BMSCs.
Huajian Shan   +10 more
wiley   +1 more source

Operational mechanism of clinical nurse specialist outpatient clinics for gastric cancer in the UK and its implications for China

open access: yesHuli yanjiu
ObjectiveTo explore the operational mechanism of the clinical nurse specialist(CNS) outpatient model for gastric cancer in the UK and to analyze its implications for the development of the gastric cancer nursing service system in China.MethodsA framework
JIANG Yi   +3 more
doaj  

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