Results 91 to 100 of about 2,699,017 (390)

A cross-sectional study exploring the relationship between burnout, absenteeism, and job performance among American nurses

BMC Nursing, 2019
BackgroundStudies suggest a high prevalence of burnout among nurses. The aim of this study was to evaluate the relationship between burnout among nurses and absenteeism and work performance.MethodsA national sample of U.S.
L. Dyrbye, T. Shanafelt, Pamela O. Johnson, L. Johnson, D. Satele, C. West   +5 more
semanticscholar   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

“We Are Our Own Worst Enemies”: Workplace Bullying Among Nurses and Its Implications on Healthcare Workers and Job Performance: A Multi‐Facility Study in the Tamale Metropolis

Nursing Open
Background Workplace bullying is an important issue confronting the nursing profession, with victims described as being part of an oppressed group. The number of attacks and acts of violence that staff direct at each other in the workplace is alarmingly ...
Abubakari Wuni, Ajara Musah, Iddrisu Mohammed Sisala, Abdul Malik Abdulai, Letitia Chanayireh, Brenda Abena Nyarko, Hannah Buasilenu, Mudasir Mohammed Ibrahim, Sulemana Musah, Dorothy Azure, Nafisah Abdulai   +10 more
doaj   +1 more source

The perspective of psychiatric nurses by the European Psychiatric Nurses (Horatio)

European Psychiatry
In the health care system, nurses are often the biggest professional group and therefore their role is important in the development of service system to meet the current needs of support and help in mental health.
N. Kilkku
doaj   +1 more source

Long-term exposure to road traffic noise and stroke incidence: a Danish Nurse Cohort study [PDF]

, 2021
Tom Cole‐Hunter, Christian Dehlendorff, Heresh Amini, Amar Mehta, Youn‐Hee Lim, Jeanette T. Jørgensen, Shuo Li, Rina So, Laust Hvas Mortensen, Rudi G. J. Westendorp, Barbara Hoffmann, Elvira V. Bräuner, Matthias Ketzel, Ole Hertel, Jørgen Brandt, Steen Solvang Jensen, Jesper Heile Christensen, Camilla Geels, Lise Marie Frohn, Claus Backalarz, Mette Kildevæld Simonsen, Steffen Loft, Zorana Jovanovic Andersen   +22 more
openalex   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Cultural Identity of Labor and Delivery Nurses In the Assessment of Pregnant Patients For Interpersonal Violence [PDF]

, 2006
Objective: Identification of barriers to assessment of interpersonal violence (IPV) in pregnant women. Design: An exploratory descriptive study Setting: The labor and delivery department of a public county hospital Participants: 34 nurses, representing 8
Smith, Ramona Nichols
core   +1 more source

Do task and item difficulty affect overestimation of one’s hand hygiene compliance? A cross-sectional survey of physicians and nurses in surgical clinics of six hospitals in Germany [PDF]

, 2022
Jonas Lamping, Ivonne Tomsic, Maike Stolz, Christian Krauth, Iris F. Chaberny, Thomas von Lengerke   +5 more
openalex   +1 more source

Prevalence and Risk Factors of Depression, Anxiety, and Stress in a Cohort of Australian Nurses

International Journal of Environmental Research and Public Health, 2018
Nurses remain at the forefront of patient care. However, their heavy workload as a career can leave them overworked and stressed. The demanding nature of the occupation exposes nurses to a higher risk of developing negative mental states such as ...
Shamona Maharaj, T. Lees, S. Lal
semanticscholar   +1 more source