Results 61 to 70 of about 886,923 (294)

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Outcomes of Simulation-Based Education on Prelicensure Nursing Students’ Preparedness in Identifying a Victim of Human Trafficking

Social Sciences
Background: Individuals who are victimized and exploited by the heinous crimes of human trafficking (HT) access healthcare during their exploitation, yet gaps in education on HT content exist in prelicensure nursing programs.
Debra McWilliams, Geraldine Cornell, Francine Bono-Neri   +2 more
doaj   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Response to “An overview of health workforce education and accreditation in Africa: implications for scaling-up capacity and quality”

Human Resources for Health, 2023
Alex Berland, Helen Ewing, Kathleen Capone, Erica Frank, Miriam Chickering   +4 more
doaj   +1 more source

Oxygen therapy: Knowledge, attitude, practices, and barriers among nurses and midwives at Tamale Teaching Hospital

International Journal of Africa Nursing Sciences
Background: Oxygen therapy is a long-standing, life-saving intervention, but its administration requires careful management to maximize benefits and reduce potential harm. Aim: This study assessed the knowledge, attitudes, practices, and barriers related
Iddrisu Mohammed Sisala, Mudasir Mohammed Ibrahim, Abdul Latif Abdul Rahaman, Firdaus Ayariga Mustapha, Ayisha Mohammed, Abubakari Wuni   +5 more
doaj   +1 more source

Commentary on Spilsbury K, Petherick E, Cullum N, Nelson A, Nixon J & Mason S (2008) The role and potential contribution of clinical research nurses to clinical trials.Journal of Clinical Nursing17, 549–557 [PDF]

, 2008
Claire M. Rickard, Brigit Roberts
openalex   +1 more source

Review for "Primary healthcare nurses’ involvement in patient and community participation in the context of chronic diseases: An integrative review"

, 2021

openalex   +1 more source

A qualitative content analysis of nurses' perceptions about readiness to manage intimate partner violence [PDF]

, 2021
Erica Briones‐Vozmediano, Laura Otero‐García, Montserrat Gea‐Sánchez, Susana De Fuentes, Marta García‐Quinto, Carmen Vives‐Cases, Amaia Maquibar   +6 more
openalex   +1 more source

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

Molecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti, Giovanni Germano, Pietro Paolo Vitiello, Alberto Bardelli   +3 more
wiley   +1 more source

Review for "Qualitative exploration of nurses' experiences of the COVID ‐19 pandemic using the Reconceptualized Uncertainty in Illness Theory: An interpretive descriptive study"

, 2021

openalex   +1 more source