Results 61 to 70 of about 1,051,472 (295)

Cytosolic‐enhanced dark Epac‐based FRET sensors allow for intracellular cAMP detection in live cells via FLIM

open access: yesFEBS Letters, EarlyView.
We describe a novel set of Epac‐based FRET‐FLIM biosensors with improved fully cytosolic distribution, achieved without compromising the state‐of‐the‐art performance of our original designs, for detecting cAMP dynamics in real time in live cells with high precision and reliability.
Giulia Zanetti   +2 more
wiley   +1 more source

Health Beliefs and Breast Cancer Screening Behavior among a Group of Female Health Professionals in Turkey

open access: yesEuropean Journal of Breast Health, 2016
Objective:The purpose of this study was to identify the health beliefs and breast cancer (BC) screening behavior of a group of female health professionals (FHPs) [physicians, nurses and midwives] in Turkey.Materials and Methods:This descriptive study was
Meryem Yılmaz, Tuğba Durmuş
doaj   +1 more source

Diphthamide synthesis is linked to the eEF2‐client chaperone machinery

open access: yesFEBS Letters, EarlyView.
The diphthamide modification of eukaryotic translation elongation factor 2 (eEF2) is important for accurate protein synthesis. We addressed the potential coordination of de novo eEF2 synthesis with simultaneous or subsequent diphthamide modification. Our work reveals that the co‐chaperones Hgh1 and Cpr7, which are known to support folding of nascent ...
Lars Kaduhr   +4 more
wiley   +1 more source

Optimizing Clinical Practice through Rigorous Integration of Scientific Evidence

open access: yesMedUNAB, 2023
This editorial provides healthcare professionals with critical reflection on the importance of evidence-based practice, as well as the challenges inherent in its implementation.
Doris Grinspun
doaj   +1 more source

Cycles through two edges in signed graphs [PDF]

open access: yesarXiv, 2023
We give a characterization of when a signed graph $G$ with a pair of distinguished edges $e_1, e_2 \in E(G)$ has the property that all cycles containing both $e_1$ and $e_2$ have the same sign. This answers a question of Zaslavsky.
arxiv  

Characterization of fungal carbonyl sulfide hydrolase belonging to clade D β‐carbonic anhydrase

open access: yesFEBS Letters, EarlyView.
Here, we performed a functional analysis of the fungal enzymes belonging to clade D of the β‐class carbonic anhydrase family (β‐D‐CA). The β‐D‐CAs in the basidiomycete Gloeophyllum trabeum and the ascomycete Trichoderma harzianum showed very low activity in the hydration of CO2 but exhibited high activity in the hydrolysis of carbonyl sulfide (COS ...
Ryuka Iizuka   +6 more
wiley   +1 more source

Prevalence and Risk Factors of Depression, Anxiety, and Stress in a Cohort of Australian Nurses

open access: yesInternational Journal of Environmental Research and Public Health, 2018
Nurses remain at the forefront of patient care. However, their heavy workload as a career can leave them overworked and stressed. The demanding nature of the occupation exposes nurses to a higher risk of developing negative mental states such as ...
Shamona Maharaj, T. Lees, S. Lal
semanticscholar   +1 more source

Elucidation of interface interactions between a dehydratase domain and an acyl carrier protein in cremimycin polyketide synthase

open access: yesFEBS Letters, EarlyView.
In modular polyketide synthases, the dehydratase (DH) domain catalyzes the dehydration reaction of the β‐hydroxyacyl unit attached to the cognate acyl carrier protein (ACP) domain. However, it is unclear how DH interacts with ACP during the reaction. In this study, we identified DH–ACP interface residues, providing the first detailed insights into DH ...
Kaede Kotagiri   +8 more
wiley   +1 more source

RNAO’s Artificial Intelligence Innovations: A Novel Strategy to Advance Evidence-Based Nursing Practice

open access: yesMedUNAB
Introduction. Artificial intelligence and machine learning methodologies, such as prediction, pattern recognition, or general inference based on the data used in clinical aspects, must fit within the intended purposes of developing it.
Naik, Shanoja, Grinspun, Doris
doaj   +1 more source

Bibliometric Profile of Nursing Research in Ex Yugoslavian Countries [PDF]

open access: yesarXiv, 2021
The development of modern nursing and consequently nursing research in Ex- Yugoslavia is about a century old. To profile the development, volume, and content of nursing research we completed a performance and spatial bibliometric analysis combined with synthetic content analysis to identify the most productive countries and institutions, most prolific ...
arxiv  

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