Results 151 to 160 of about 245,699 (265)

Navigating adverse immunostimulation: A practical guide for clinical researchers

British Journal of Clinical Pharmacology, EarlyView.
Problem Setting As drug development moves towards more complex products, early clinical development programmes are increasingly hampered by unwanted and/or unexpected activation of the immune system (adverse immune stimulation, AIS). Solution At the Centre for Human Drug Research, we have introduced standardized procedures to make AIS manageable, while
Juliette A. van den Noort, Anouk C. Meijs, Naomi B. Klarenbeek, Matthijs Moerland   +3 more
wiley   +1 more source

Implementation of the Registered Nurses' Association of Ontario Best Practice Guidelines for delirium-specific recommendations in a digital practice setting at Humber River Health, Canada. [PDF]

Int J Nurs Sci
Yoon J, Hutchinson D, Ghuman A, Maghera G, Edelstein B, Soogree R, Payumo M, Mercieca G, Goguen S, Leblanc E, Plathanathu A, Sud A, Collins BE, Neagu T, Zuk A.   +14 more
europepmc   +1 more source

Age‐related differences in hydroxychloroquine‐associated adverse events: A pharmacovigilance study based on the FDA Adverse Event Reporting System

British Journal of Clinical Pharmacology, EarlyView.
Aims This real‐world pharmacovigilance study utilizes FDA Adverse Event Reporting System (FAERS) data (2004–2024) to characterize age‐related disparities in hydroxychloroquine (HCQ)‐associated adverse events (AEs), addressing gaps in age‐stratified risk assessment. Methods Disproportionality analysis (reporting odds ratios, RORs) and parametric Weibull
Guanghan Sun, Jingrong Yang, Lei Wan, Xia Xu, Jing Wang   +4 more
wiley   +1 more source

Population pharmacokinetics of levofloxacin in breastmilk in patients with rifampicin‐resistant tuberculosis

British Journal of Clinical Pharmacology, EarlyView.
Levofloxacin is a widely used antibiotic included in rifampicin‐resistant tuberculosis (RR‐TB) treatment. Data describing levofloxacin concentrations in breastmilk and infant exposure are limited. We analysed data from two South African studies of breastfeeding women receiving levofloxacin (750–1000 mg daily) for RR‐TB.
Sharon Sawe, Lufina Tsirizani, Buyisile Mkhize, Lubbe Wiesner, Gary Maartens, Francesca Conradie, Richard Court, Marian Loveday, Catriona Waitt, Paolo Denti   +9 more
wiley   +1 more source

Evaluation of Intravenous Administration of Anti-Infective Agents and Documentation Quality in Orthopedics and Trauma Surgery: A Quantitative Study on Discrepancies Between Physician Prescriptions and Nursing Records. [PDF]

Antibiotics (Basel)
Dahse AJ, Klimpel L, Heinitz K, Neininger MP, Lübbert C, Huke A, Kleber C, Roth A, Pempe C, Notov D, Hepp P, Heyde CE, Bertsche T, Remane Y.   +13 more
europepmc   +1 more source

Safety concerns reported by coroners following fentanyl patch fatalities in England, Wales and Northern Ireland between 1997 and 2024

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim To identify safety concerns reported by coroners following fentanyl patch‐related deaths in England, Wales and Northern Ireland, and determine differences in coronial reporting. Methods A systematic case series linking the National Programme on Substance Use Mortality (NPSUM) and the Preventable Deaths Tracker (PDT) (https ...
Eman Mshari, Caroline S. Copeland, Georgia C. Richards   +2 more
wiley   +1 more source

Effect of 6S refined individualized nursing management in the perioperative period of Parkinson's disease patients undergoing deep brain stimulation. [PDF]

Front Neurol
Luo Y, Guo F, Bai J, Li X, Bei J, Xing Y, Zhang F.   +6 more
europepmc   +1 more source

Nurse Administrator [PDF]

, 2020
openaire   +1 more source

Risk of venous thromboembolism after SARS‐CoV‐2 vaccination—Evidence from genome‐wide association study and population‐based observational study

British Journal of Clinical Pharmacology, EarlyView.
Aim We aimed to investigate whether genetic variation is associated with venous thromboembolism after immunization with SARS‐CoV‐2 vaccines. Methods We conducted a genome‐wide association study (GWAS) on cases of venous thromboembolism within 42 days after SARS‐CoV‐2 vaccination, recruited from reports of adverse drug reactions sent to the Swedish ...
Sofia Attelind, Niclas Eriksson, Marco Cavalli, Yiyi Xu, Fredrik Nyberg, Anders Sundström, Mia Wadelius, Pär Hallberg   +7 more
wiley   +1 more source

Correction: Fostering green transformational leadership: the influence of green educational intervention on nurse managers’ green behavior and creativity

BMC Nursing
Manal Saleh Moustafa Saleh, Hanan Elsaid Elsabahy, Sahar Abdel-Latif Abdel-Sattar, Zaineb Naiem Abd-Elhamid, Abdulellah Al Thobaity, Sahar Mohammed Mohammed Aly, Wafaa Mohamed Shokry   +6 more
doaj   +1 more source