Targeting Endothelial KDM5A to Attenuate Aging and Ameliorate Age‐Associated Metabolic Abnormalities
This study identifies endothelial KDM5A as a key regulator of aging. KDM5A deficiency accelerates aging by enhancing H3K4me3‐mediated FABP4 expression, disrupting fatty acid metabolism, and promoting multi‐organ senescence. KDM5A restoration or FABP4 inhibition reverses these adverse effects and extends lifespan, positioning the KDM5A/FABP4 axis as a ...
Rifeng Gao +21 more
wiley +1 more source
How Nurse Express Their Caring Behavior to Patients with Special Needs (Research Report) [PDF]
The purpose of the research was to explore how nurses who work in the specific nursing care facilities express their caring behavior to patients with special needs.
Nurachmah, E. (Elly)
core +2 more sources
This study constructs a proteomic atlas of esophageal squamous cell carcinoma (ESCC) progression using esophageal biopsy samples. It identifies moderate dysplasia as the critical turning stage and a seven‐protein panel for early detection. Functionally, GBP6 loss promotes ESCC progression via cell cycle and epithelial‐mesenchymal transition (EMT ...
Xumiao Li +12 more
wiley +1 more source
What is the potential of distance education for learning and practice development in critical care nursing in the South Island of New Zealand? : a thesis presented in partial fulfilment of the requirements for the degree of Master of Education in Adult Education at Massey University [PDF]
This thesis explores the potential of distance approaches to teaching and learning in post registration nursing education within the context of critical care nursing practice.
Hardcastle, Jane
core
Indian nurses in Italy: a qualitative study of their professional and social integration [PDF]
AIMS AND OBJECTIVES: To investigate the lived subjective experiences of immigrant Indian nurses in Italy and specifically their professional and social integration.
Olsen, D +4 more
core +1 more source
PATIENT SAFETY: ANALYSIS OF RESEARCH GROUPS
The present study aimed to assess the characteristics of research groups of theBrazilian National Council for Scientific and Technological Development specialized in patient safetyin health and nursingfields. Documentary, descriptive exploratory study of
Aline Natalia Domingues +2 more
doaj +1 more source
This study presents an impedance‐based single‐cell profiling platform that quantifies the electrical and mechanical properties of neutrophils across in vitro, in vivo, and clinical samples. The approach reveals distinct biophysical alterations associated with type 2 diabetes (T2DM) and cardiovascular complications, suggesting its potential utility for ...
Linwei He +13 more
wiley +1 more source
Academic achievement in public higher education quality – A study on the effects of teachers’ commitment, teaching and evaluation methodologies in Nursing and Management degrees students. [PDF]
The huge development of science and technology and the political, social and economic changes that characterize post-modern societies, demand from education systems a quality formation for all citizens. The great challenge of the XXI century in education
Bonito, Jorge +7 more
core
Collaborating with Businesses to Support and Sustain Research [PDF]
Financial assistance is necessary for sustaining research at universities. Business collaborations are a potential means for obtaining these funds. To secure funding, understanding the process for obtaining these business funds is important for nursing ...
Jadack, Rosemary A. +4 more
core +2 more sources
GOT1 Inhibition Induces Extracellular Matrix Remodeling in Pancreatic Cancer
Using tumor tissue engineering, we recreated pancreatic cancer and found that inhibiting glutamic‐oxaloacetic transaminase 1 (GOT1) induces extracellular matrix remodeling and secretome rewiring, as well as promotes cell death. ABSTRACT Pancreatic cancer cells rely on glutamine to sustain their survival in the stiff and poorly vascularized tumor ...
Rodrigo Curvello +10 more
wiley +1 more source

