Results 181 to 190 of about 2,592,587 (304)

Phase I Evaluation of Siltartoxatug, a First‐in‐Class Anti‐Tetanus Monoclonal Antibody: Safety, Pharmacokinetics and Pharmacodynamics in Healthy Australian and Chinese Populations

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Siltartoxatug, a first‐in‐class monoclonal antibody targeting tetanus toxin for post‐exposure prophylaxis, was evaluated in two phase I trials in Australian and Chinese healthy adults. In these randomized, double‐blind, placebo‐controlled, dose‐escalation studies, participants received a single intramuscular injection of siltartoxatug (10–250 μg/kg) or
Xinyu Liu   +15 more
wiley   +1 more source

Investigation of Quiet Quitting and Professional Quality of Life Among Nursing Staff at a General Hospital: A Single-Site Cross-Sectional Study. [PDF]

open access: yesHealthcare (Basel)
Rovithis M   +6 more
europepmc   +1 more source

Model‐Informed Dose Optimization of Anakinra in Preterm Neonates Implications for Safe and Effective Dosing

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Anakinra, an interleukin‐1 receptor antagonist, shows promise for reducing inflammatory complications of premature birth. However, the pharmacokinetics (PK) of anakinra in neonates has not been characterized, limiting evidence‐based dosing. This study aimed to develop a population PK model for anakinra to guide dosing in preterm neonates.
Jia Li   +27 more
wiley   +1 more source

Navigating the Role of Clinical Pharmacists in Integrative Oncology Care Teams: Time to Create Higher Training and Practice Standards

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Integrative oncology (IO) programs are committed to offer evidence‐based complementary medicine within conventional cancer care, addressing quality of life‐related concerns. As part of a multidisciplinary team, clinical pharmacists provide guidance on potential effectiveness and safety of herbal supplement use, identifying potential toxicities and herb–
Eran Ben‐Arye   +3 more
wiley   +1 more source

Balancing Impartiality and Advocacy: Observations, Lessons, and Suggestions From a Practicing Ombuds

open access: yesConflict Resolution Quarterly, EarlyView.
ABSTRACT Universities increasingly rely on ombuds offices as informal, impartial mechanisms for addressing conflict and strengthening institutional trust. Yet the ombuds role is frequently shaped by tension among impartiality, advocacy, and legal accountability. This paper examines the evolution of the Office of the Ombuds at the University of Maryland,
Brian Godette, Roger Ward, Leandra Cate
wiley   +1 more source

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