Results 211 to 220 of about 6,443,677 (299)

Phase I Evaluation of Siltartoxatug, a First‐in‐Class Anti‐Tetanus Monoclonal Antibody: Safety, Pharmacokinetics and Pharmacodynamics in Healthy Australian and Chinese Populations

Clinical Pharmacology &Therapeutics, EarlyView.
Siltartoxatug, a first‐in‐class monoclonal antibody targeting tetanus toxin for post‐exposure prophylaxis, was evaluated in two phase I trials in Australian and Chinese healthy adults. In these randomized, double‐blind, placebo‐controlled, dose‐escalation studies, participants received a single intramuscular injection of siltartoxatug (10–250 μg/kg) or
Xinyu Liu, Zhigang Liu, Xiaohu Kuang, Yueming Wang, Xiaoyi Liu, Jiyuan Ding, Xia Zhou, Xin Zhou, Qianyu Liang, Meizhuo Zhang, Hao Zhao, Qingqing Tan, Weihong Zheng, Huaxin Liao, Charlotte Lemech, Wanmei Wang   +15 more
wiley   +1 more source

Nurses' Perspectives on a Communication Model Between Providers and Mechanically Ventilated Patients in the Intensive Care Unit. [PDF]

Nurs Crit Care
Karlsen MW, Heyn LG, Kvande ME, Dreyer P, Tate JA, Happ MB, Holm A.   +6 more
europepmc   +1 more source

Model‐Informed Dose Optimization of Anakinra in Preterm Neonates Implications for Safe and Effective Dosing

Clinical Pharmacology &Therapeutics, EarlyView.
Anakinra, an interleukin‐1 receptor antagonist, shows promise for reducing inflammatory complications of premature birth. However, the pharmacokinetics (PK) of anakinra in neonates has not been characterized, limiting evidence‐based dosing. This study aimed to develop a population PK model for anakinra to guide dosing in preterm neonates.
Jia Li, David K. Metz, Elys Green, Gergely Toldi, Robert Galinsky, Megan Clark, Rebecka Atkinson, Ina Rudloff, Josephine C. Owen, Sara K. DiSimone, Samuel C. Forster, Steven X. Cho, Atif Majid, Graeme R. Polglase, Marcel Favilla, Pramod Pharande, Atul Malhotra, Calum T. Roberts, Scott H. Stansfield, Arvind Sehgal, Kenneth Tan, Alistair J. Gunn, Philip J. Berger, Alex Veldman, Rod W. Hunt, Claudia A. Nold‐Petry, Marcel F. Nold, Carl M. J. Kirkpatrick   +27 more
wiley   +1 more source

Balancing tradition, modernity, and spirituality: A grounded theory of non-communicable disease management in the Tai Saek Ethnic Group of Thailand. [PDF]

Belitung Nurs J
Sangsaikaew A, Ruaisungnoen W.
europepmc   +1 more source

The Role of Humble Leadership in Corporate Social Responsibility and Sustainable Human Resource Management

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT This study examines the relationship between humble leadership and employee deviance in uncertain organizational environments, with a focus on the moderating role of employee mindfulness and the mediating role of basic psychological needs, as framed by self‐determination theory (SDT).
Ma Zixian, Muhammad Zeshan, Shahid Rasool, Muhammad Faisal Rasheed, Giuseppe Liccardo, Roberto Cerchione   +5 more
wiley   +1 more source

Happy and helpful: relationship of authentic leadership with employees helping behaviors: the mediating role of hedonic and eudaimonic wellbeing among nursing staff. [PDF]

BMC Nurs
Farid T, Iqbal S, Algarni MA, Raheem M, Ullah Z, Ali SR.   +5 more
europepmc   +1 more source

From Data to Action: The Role of Reports and Certifications in Driving Corporate Sustainability

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT Corporate sustainability has become a central issue for businesses, driven by environmental, social and governance pressures and stakeholder expectations. The present study aimed to assess how reports and certifications influence motivations, operational practices and perceptions of obstacles, verifying whether these tools promote sustainable ...
Stefano Cianciotta, Idiano D'Adamo, Alfredo De Massis, Massimo Gastaldi, Nicolò Laganà   +4 more
wiley   +1 more source

Not Yet Epistemic: Re-Reading Barbara Carper's Patterns of Knowing. [PDF]

Nurs Inq
Bender M.
europepmc   +1 more source

Internationalising the teacher education curriculum: An analysis of syllabi and student experiences

The Curriculum Journal, EarlyView.
Abstract Internationalisation has increasingly become a key dimension of quality in initial teacher education (ITE) programmes. Although it is recognised as a means to strengthen future teachers' competencies and expand their professional knowledge, it remains underdeveloped in practice.
Nafsika Alexiadou, Mai Trang Vu
wiley   +1 more source

Predictors of nursing students' satisfaction with the clinical learning environment in Kosovo: A multivariate analysis using the Clinical Learning Environment, Supervision and Nurse Teacher framework. [PDF]

Belitung Nurs J
Oruqi M, Petrela E, Gashi H.
europepmc   +1 more source