Results 51 to 60 of about 713,334 (308)

A Fungi-Driven Sustainable Circular Model Restores Saline Coastal Soils and Boosts Farm Returns

open access: yesHorticulturae
Agricultural production in the saline–alkaline soils of the Yellow River Delta faces persistent challenges in waste recycling and soil improvement. We developed a three-stage circular agriculture model integrating “crop straw–edible mushrooms–vegetables,”
Fei Bian   +9 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Synergistic Application of Humic Acid and Microbial Fertilizers Improve Soil Quality, Reshape Microbial Network, and Enhance Wheat Yield in Coastal Saline–Alkali Soils

open access: yesMicroorganisms
Coastal saline–alkali soils represent one of the most challenging agroecosystems due to coupled chemical, physical, and biological constraints. Although humic acid (HA) and microbial fertilizers (MFs) are recognized as effective amendments, the ...
Lei Ma   +6 more
doaj   +1 more source

Biogas nutrient management in organic cropping - not only a nitrogen issue [PDF]

open access: yes, 2013
Nutrient imbalance, mainly due to low K and high Ca and/or Mg concentrations, was a plausible explanation for low growth response to digestate fertilisation by beetroot following harvested grass-clover biogas ley.
Asp, H., Gunnarsson, A.
core  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Maize yield in a strip-till system can be increased by increasing nitrogen accumulation, plant growth, and ear development around silking stage in Northeast China

open access: yesCrop Journal
Strip-till (ST), including straw mulching in the inter-row and localized fertilization in the intra-row, is a conservation tillage system for improving soil quality and crop growth.
Ye Sha   +9 more
doaj   +1 more source

Reducing the external environmental costs of pastoral farming in New Zealand: experiences from the Te Arawa lakes, Rotorua [PDF]

open access: yes, 2011
Decades of nutrient pollution have caused water quality to decline in the nationally iconic Te Arawa (Rotorua) lakes in New Zealand. Pastoral agriculture is a major nutrient source, and therefore this degradation represents an external environmental cost
Abell, Jonathan Michael   +2 more
core   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Agriculture, meteorology and water quality in Ireland: a regional evaluation of pressures and pathways of nutrient loss to water [PDF]

open access: yes, 2006
peer-reviewedThe main environmental impact of Irish agriculture on surface and ground water quality is the potential transfer of nutrients to water. Soil water dynamics mediate the transport of nutrients to water, and these dynamics in turn depend on ...
Daly, Karen M.   +5 more
core   +1 more source

Strategies to reduce nutrient pollution from manure management in China [PDF]

open access: yes, 2020
As the demand for livestock products continues to increase in China, so too does the challenge of managing increasing quantities of manure. Urgent action is needed to control point source (housing, storage and processing) and diffuse (field application ...
Bai, Zhaohai   +7 more
core   +2 more sources

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