Results 231 to 240 of about 2,037,294 (290)

Targeted Restoration of the Microbial Tryptophan Oxidative Pathway Ameliorates Autism‐Like Behavioral and Synaptic Deficits

Advanced Science, EarlyView.
ABSTRACT Autism Spectrum Disorder (ASD) is associated with gut microbiota dysbiosis, yet the contribution of specific microbial metabolic pathways remains unclear. Reanalysis of a public ASD cohort revealed reduced functional potential in microbial tryptophan oxidative metabolism.
Rui Guo, Caian He, Xiao Xiao, Jingmeng Li, Zilong Zhang, Ying He, Chuanchuan Wang, Jiale Zhao, Jun Gong, Jiarui Liang, Tian Yuan, Haiting Sun, Xuebo Liu, Chao Gao, Zhigang Liu   +14 more
wiley   +1 more source

Thymosin Alpha‐1 Provides Direct Neuroprotection by Engaging the Orexin Receptor HCRTR1 to Suppress Neuronal Necroptosis

Advanced Science, EarlyView.
In this study, we unveil a thymus‐brain endocrine axis wherein Tα1 engages HCRTR1 to inhibit RIPK3‐mediated necroptosis. This study nominates the Tal‐HCRTR1‐RIPK3 axis as a potent and clinically translatable therapeutic target for stroke and neurodegeneration.
Xinmei Kang, Shisi Wang, Liubin Zhang, Mengyan Hu, Xiaotao Su, Yuxin Liu, Qin Qin, Haotong Yi, Liling Yuan, Wei Cai, Lei Wei, Zhengqi Lu   +11 more
wiley   +1 more source

Nutrient Sensing, Monitoring, and Control for Hydroponic Crop Production in Smart Greenhouses. [PDF]

Sensors (Basel)
Majumder A, Reza MN, Robin S, Kang JY, Lee S, Choi H, Noh DH, Chung SO.   +7 more
europepmc   +1 more source

Co‐Delivery of Sustained Release Chondroitinase ABC‐37 With Human iPSC‐Derived Neural Progenitors Promotes Transplant Survival and Functional Recovery in a Rodent Model of Stroke

Advanced Science, EarlyView.
A regenerative strategy for stroke combines human stem cell–derived neural progenitor cells with sustained release of a matrix‐modifying, thermostable chondroitinase ABC‐37 enzyme. In a rat model of stroke, co‐delivery enhanced transplanted cell survival and neuronal differentiation, degraded inhibitory extracellular matrix components, and improved ...
Nitzan Letko Khait, David Xinzheyang Li, Keyi Guo, Hong Cui, Quinton Sirianni, Dhana Abdo, Cindi M. Morshead, Molly S. Shoichet   +7 more
wiley   +1 more source

Closing the micronutrient loop: recovering and redirecting trace elements from food supply chains for a circular and nutrition-secure future. [PDF]

Front Nutr
He S, Wu Y, Jellicoe M, Yang J.
europepmc   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

The Plant-Microbe Alliance for Environmental Restoration: From Nature-Inspired Solutions to Engineered Ecological Recovery. [PDF]

Microb Biotechnol
Molina L, González-Pagán L, Segura A.
europepmc   +1 more source

Using mass-balance principles to optimize nutrition of lettuce. [PDF]

Front Plant Sci
Langenfeld NJ, Bugbee B.
europepmc   +1 more source

Plants and low oxygen: from sensing and signalling to ecological adaptation and crop resilience. [PDF]

J Exp Bot
Fukao T, Ashikari M, Nakazono M.
europepmc   +1 more source

Integrated Algal Bioenergy Platforms: Advances in Microbial Fuel Cell Integration and Nanotechnology-Enabled Biorefineries. [PDF]

Nanomaterials (Basel)
Mohamed YS, Steele S, Khafaga DSR, Basem Y, Shawky AM, Mostafa YG, Solyman SM.   +6 more
europepmc   +1 more source