Results 51 to 60 of about 189,010 (263)

Targeting Nutrient Uptake Mechanisms in Plasmodium

open access: yesCurrent Drug Targets, 2007
The proliferation of the intraerythrocytic malaria parasite is dependent on the uptake from the blood plasma, and from the cytoplasm of the host cell, of a range of essential nutrients. These compounds are taken up into the parasitised cell via a combination of constitutively active endogenous host cell transporters and new parasite-induced ...
Kirk, Kiaran, Saliba, Kevin
openaire   +3 more sources

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

A mathematical model of plant nutrient uptake

open access: yesJournal of Mathematical Biology, 2001
The classical model of plant root nutrient uptake due to Nye. Tinker and Barber is developed and extended. We provide an explicit closed formula for the uptake by a single cylindrical root for all cases of practical interest by solving the absorption-diffusion equation for the soil nutrient concentration asymptotically in the limit of large time.
Roose, T, Fowler, A, Darrah, P
openaire   +6 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Yield, nutrient uptake, and nutrient use efficiency of chickpea under altered soil surface management practices in vertisols of Western India

open access: yesFrontiers in Agronomy
Low nutrient use efficiency in intensive cropping system leads to economic loss and environmental degradation, through nutrient runoff and leaching. Sustainable soil surface management techniques modify soil properties, enhance in-situ soil and water ...
Anita Kumawat   +7 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Nutrient dynamics in restored and unrestored urban streams in the Piedmont ecoregion of South Carolina

open access: yesFrontiers in Environmental Science
The United States invests billions of dollars annually to perform stream restoration projects, yet few studies have investigated the effects this ecosystem manipulation has on nutrient cycling and associated water quality.
Emily N. Jordan   +6 more
doaj   +1 more source

Direct and residual effect of various vermicompost on soil nutrient and nutrient uptake dynamics and productivity of four mustard Pak-Coi (Brassica rapa L.) sequences in organic farming system

open access: yesInternational Journal of Recycling of Organic Waste in Agriculture, 2018
Purpose To study the direct effect on the first mustard cropping and the residual effect of three kinds of vermicompost on the productivity of the second, third, fourth Pak-Coi mustard sequential cropping. Method A field experiment was conducted for four
N. Nurhidayati   +2 more
doaj   +1 more source

The growth and nutrient uptake of winter wheat

open access: yesPlant and Soil, 1978
Measurements with an ion selective electrode under winter wheat and in adjacent fallow soil, from April to July 1976, showed that nitrate concentrations were high in the 0–25 cm zone and correspondingly lower at 50 cm, because of the extreme drying conditions.
Page, M. B.   +2 more
openaire   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

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