Leaky Gut’s Contribution to Inefficient Nutrient Utilization
There are a variety of situations in an animal’s life when nutrient utilization is reprioritized from productive towards agriculturally unproductive purposes. Two well-known examples that markedly reduce production are heat stress and ketosis.
Keating, Aileen +7 more
core
Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende +26 more
wiley +1 more source
Dietary β-mannanase supplementation and its effect on nutrient utilization and performance in broilers fed energy-reduced diets. [PDF]
Choi SD +7 more
europepmc +1 more source
Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett +8 more
wiley +1 more source
Effects of Betaine on Performance, Blood Biochemistry, Nutrient Utilization and Gut Health in Coccidia-Infected Broilers. [PDF]
Hafeez A +6 more
europepmc +1 more source
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao +6 more
wiley +1 more source
Comparative evaluation of phytate and phytase addition on growth performance and nutrient utilization efficiency in broilers and ducks. [PDF]
Pirzado SA +4 more
europepmc +1 more source
To study the effect of supplementation of antibiotic, prebiotic and an enzyme mixture on growth and nutrient utilization, 48 day-old chicks were divided into 4 groups (6 males, 6 females) and fed on, a standard ration with either no supplementation (C ...
Acikgoz, Z, Kirkpinar, F
core
ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
Effect of yeast fermentation on nutrient utilization and growth performance of broilers fed commercial and hand-mixed diets. [PDF]
Islam S +5 more
europepmc +1 more source

