In an invasive beetle–fungus complex, the mutualist Leptographium procerum induces host HSP83 and modulates Toll‐dependent antifungal immunity. HSP83 mediates two‐tiered control by associating with selected fungal recognition receptors and restraining Dorsal‐driven antimicrobial peptide transcription.
Qingtai Yang +8 more
wiley +1 more source
Tickborne diseases of the United States : a reference manual for health care providers. Second edition, 2014. [PDF]
First ed., 2013.Based on \u201cTickborne Diseases in Massachusetts: A Physician\u2019s Reference Manual\u201d, produced by collaboration between MDPH, Nancy Shadick, MD, MPH, and Nancy Maher, MPH of the RBB Arthritis and Musculoskeletal Diseases Clinical
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The Role of Immunological Challenges, Oxidative Stress, and Dietary Interventions in Managing Hashimoto's Thyroiditis: A Narrative Review. [PDF]
Morasiewicz-Jeziorek J +3 more
europepmc +1 more source
OAF Blocks SIAH1‐Mediated Degradation of SCPX, a Therapeutic Strategy for MASLD
This study shows OAF directly binds to SCPX and inhibits its interaction with the E3 ligase SIAH1, thereby protecting SCPX from ubiquitin‐dependent degradation and stabilizing its levels. This OAF‐SCPX axis represents a novel pathway in lipid homeostasis, highlighting OAF as a promising therapeutic candidate for MASLD.
Zongxi Li +11 more
wiley +1 more source
Micronutrients in Pediatric Asthma: Biological Mechanisms and Clinical Evidence-A Narrative Review. [PDF]
Chereches-Panta P +6 more
europepmc +1 more source
Spatiotemporal Multi‐Omic Mapping Reveals Liver‐Muscle Metabolic Crosstalk in Cancer Cachexia
The interactive CCAtlas platform delineates cross‐species, spatiotemporal, and sex‐specific molecular dynamics and metabolic rewiring across organs during cancer cachexia. Hepatic Gamt downregulation curtails hepatic creatine synthesis to trigger systemic creatine insufficiency and consequent skeletal muscle atrophy in LLC tumour‐bearing mice ...
Zihan Tian +12 more
wiley +1 more source
Tickborne diseases of the United States : a reference manual for health care providers. Third edition, 2015. [PDF]
Based on \u201cTickborne Diseases in Massachusetts: A Physician\u2019s Reference Manual\u201d, produced by collaboration between MDPH, Nancy Shadick, MD, MPH, and Nancy Maher, MPH of the RBB Arthritis and Musculoskeletal Diseases Clinical Research Center
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Vitamin D Status in Children with Primary Immunodeficiency Disorders Receiving Vitamin D Supplementation: A Retrospective Cross-Sectional Study. [PDF]
Dąbrowska-Leonik N +6 more
europepmc +1 more source
Tumor Exposomics: A New Paradigm for Individualized Continuous Exposure Monitoring
Tumor exposomics integrates continuous monitoring of environmental exposures, endogenous biological responses, and behavioral factors within a unified temporal framework. By combining multimodal sensing technologies with AI‐enabled causal modeling, this emerging paradigm reconstructs exposure‐damage trajectories and supports individualized dynamic risk
Kaicheng Shen +6 more
wiley +1 more source
The Foodborne Diseases Active Surveillance Network (FoodNet) is a collaborative network established in cooperation with the Centers for Disease Control and Prevention\u2019s Emerging Infections Program (EIP); state health departments in California ...
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