Results 161 to 170 of about 3,094,935 (306)

CDC's neglected tropical diseases program [PDF]

Neglected tropical diseases (NTDs) are a group of infectious diseases that cause devastating illness for more than one billion people. Affecting the world\u2019s poorest people, NTDs cause disabilities that make it difficult to succeed in school, care ...

core  

Efficacy and safety of limb distalization after Roux-en-Y gastric bypass: a retrospective cohort study. [PDF]

Front Surg
Rodrigues E, Bandeira M, de Almeida RF, Nora M, Monteiro MP, Pereira SS, Guimarães M.   +6 more
europepmc   +1 more source

The GPX3‐VCAM1 Axis Gates Pro‐Fibrotic Tubule Cell Fate in Hyperuricemic Nephropathy

Advanced Science, EarlyView.
Hyperuricemia induces NLRP3 inflammasome signaling activation and downregulation of GPX3 in proximal tubular epithelial cells, leading to oxidative stress–driven VCAM1 upregulation, emergence of pro‐fibrotic proximal tubule cells, macrophage recruitment, and renal fibrosis.
Yunfei Qi, Qiang Zhao, Yue Lve, Yaming Yuan, Tingting Zhou, Yue Yuan, Dexi Wu, Yifan Tang, Yan Liu, Zhigang Li, Chunping Jiang, Qiurong Ding   +11 more
wiley   +1 more source

Exploring the impact of nutrition and autophagy on infectious diseases to inform the development of homeostatic-nanomedicines for HIV-TB coinfections. [PDF]

Discov Nano
Maphasa RE, Rambharose S, Chigorimbo-Murefu N, Fielding BC, Dube A.   +4 more
europepmc   +1 more source

Towards a Compositional Framework for Describing Human Phenotypes

Advanced Science, EarlyView.
The Phenotype Assembly Method (PhenoAM) decomposes phenotype variables into measurable Features and typed Qualifiers, enabling standardized, machine‐readable Phenome Data Elements (PhenoDEs) that preserve measurement context. Applied in the International Human Phenome Project (IHPP), the framework yields 58 371 PhenoDEs and supports component‐level ...
Wanting Hu, Yunchao Ling, Xinyue Hu, Wei Chen, Rong Zhou, Xinhao Zhuang, Yanfeng Jiang, Jialu Zhao, Xingdong Chen, Jingchun Luo, Li Jin, Guoqing Zhang   +11 more
wiley   +1 more source

COVID-19 and long-term risk of incident laboratory-defined micronutrient deficiency in patients with type 2 diabetes: a multicenter propensity score-matched cohort study. [PDF]

Front Nutr
Chen IW, Chang LC, Hung KC.
europepmc   +1 more source

Sjogren's Disease Associated with a Nutritional Deficiency Syndrome [PDF]

BMJ, 1950
openaire   +2 more sources

Adhesion‐Enhanced Engineered Probiotic for Prolonged Intestinal Retention and Calprotectin‐Responsive IBD Therapy

Advanced Science, EarlyView.
An intelligent engineered probiotic platform is developed for the precision management of inflammatory bowel disease. By integrating surface‐displayed adhesins with an inflammation‐responsive CAT‐SOD‐GPx tripartite fusion system and mucosal repair factors, this programmable system achieves prolonged intestinal retention and multi‐pronged therapy.
Yuxi Wang, Peichao Zhang, Simin Gu, Hongyun Lu, Ningning Jiang, Jiarun Zhao, Enbo Xu, Xiayu Liu, Ying Shi, Qihe Chen   +9 more
wiley   +1 more source

The hope for neglected diseases: R&D incentives [PDF]

Neglected diseases are neglected because they cannot generate enough return on R&D to pharmaceutical firms. This paper analyzes and compares existing proposals for public intervention in R&D for neglected diseases.
Brigitte Granville, Eshref Trushin
core  

Vitamins and Human Health: 3rd Edition Editorial. [PDF]

Nutrients
Guettler M, Barker T.
europepmc   +1 more source