Results 161 to 170 of about 10,963,897 (387)

Construction of a Multitissue Cell Atlas Reveals Cell‐Type‐Specific Regulation of Molecular and Complex Phenotypes in Pigs

open access: yesAdvanced Science, EarlyView.
This research conducts an in‐depth investigation of cell‐type‐specific regulatory mechanisms underlying molecular and complex phenotypes through integrative analysis of multitissue single‐nucleus RNA sequencing, bulk RNA‐seq, and genome‐wide association study (GWAS) data in pigs.
Lijuan Chen   +31 more
wiley   +1 more source

Fisheries and Aquaculture and Their Potential Roles in Development: An Assessment of the Current Evidence [PDF]

open access: yes, 2013
Commissioned by the International Sustainability Unity, this report investigates a number of innovative solutions that have been developed to deal with five key challenges that are impeding progress in achieving sustainable fisheries: overcapacity ...
Carl Harris   +6 more
core  

Gut Microbial Genetic Variation Prolongs Host Healthy Longevity and Remodels Metabolome and Proteome in Drosophila Melanogaster

open access: yesAdvanced Science, EarlyView.
This study reveals that specific genetic variations in gut‐residing Saccharomyces cerevisiae significantly extend healthspan and lifespan in Drosophila melanogaster. These mutants rejuvenate aged intestinal metabolism, upregulate mitochondrial proteins, and enhance energy pathways.
Liying Wang   +11 more
wiley   +1 more source

Food and nutrition security in Timor-Leste [PDF]

open access: yes, 2013
This report is a literature review on Food and Nutrition Security in Timor-Leste based on data from surveys conducted by the Timor-Leste National Statistics Directorate, as well as from national and international organizations working in Timor-Leste ...
Andersen, A.B., Pant, J., Thilsted, S.H.
core  

Nutrition-sensitive value chains from a smallholder perspective: A framework for project design [PDF]

open access: yes, 2020
"The Alliance of Bioversity International and the International Center for Tropical Agriculture (CIAT) gratefully acknowledges permission from IFAD to re-publish that work as an Alliance Working Paper, with updated acknowledgements, author information ...
Garrett, James   +2 more
core  

Plant Virus‐Induced Inheritable Apoptosis Drives Reproductive Costs in Female Insect Vectors to Balance Viral Biparental Transmission

open access: yesAdvanced Science, EarlyView.
Rice gall dwarf virus (RGDV), transmitted biparentally by leafhopper vector to their offspring, exploits the capsid protein to induce inheritable ovarian apoptosis via insulin‐driven PI3K/AKT/FoxO signaling axis. This mechanism enhances infection but reduces female reproductive fitness, causing inefficient maternal transmission.
Haibo Wu   +6 more
wiley   +1 more source

Adenylosuccinate Synthase 1 Deficiency Improves Energy Metabolism by Promoting Adipose Tissue Re‐esterification via Glycerol Kinase Upregulation

open access: yesAdvanced Science, EarlyView.
Working model of Adss1‐mediated regulation of energy metabolism in adipose tissue. In beige adipocytes, Adss1 interacts with HDAC3 in the cytoplasm, and its loss reduces nuclear HDAC3 while increasing cytosolic fractions. This redistribution suppresses HDAC activity and enhances H3K27 acetylation at the Gk promoter, leading to transcriptional ...
Jingjing Sun   +16 more
wiley   +1 more source

FMO2 Promotes Angiogenesis via Regulation of N‐Acetylornithine

open access: yesAdvanced Science, EarlyView.
This study identifies flavin‐containing monooxygenase 2 (FMO2) as a novel proangiogenic regulator in endothelial cells. Targeted FMO2 ablation impairs vessel sprouting, whereas its compensation potently enhances angiogenesis. Metabolomics and single‐cell sequencing reveal that FMO2 drives vascular growth via the N‐acetylornithine/ATF3/NOTCH1 axis ...
Jingyi Wang   +15 more
wiley   +1 more source

Development of strategies to improve quality and safety and reduce cost of production in organic and ‘low input‘ crop production systems [PDF]

open access: yes, 2007
The overall aims of organic and low input crop production include the economically viable and environmentally sound production of high quality food and feed.
Cohen, Y.   +3 more
core  

Home - About - Disclaimer - Privacy