Results 111 to 120 of about 773,531 (311)

Cis‐ and Trans‐Regulatory Factors Independently Shape Phenotypic Heterogeneity of Retinitis Pigmentosa

Advanced Science, EarlyView.
A zebrafish model carrying an identical human RHO S334X allele reveals two independent genetic layers shaping retinitis pigmentosa (RP) severity: a protective 3‐bp cis‐regulatory insertion that attenuates transgene expression, and a dominant trans‐acting modifier that restores a severe phenotype.
Cong Cui, Kotone Nakagawa, Takumi Tateno, Ayaka Dan, Dexin Meng, Yoshihiro Omori, Soma Tomihara, Suzuri Okamoto, Shigeru Sato, Motokazu Tsujikawa   +9 more
wiley   +1 more source

Plant Genetic Engineering: Technological Pathways, Application Scenarios, and Future Directions

Advanced Science, EarlyView.
This review maps the fast‐evolving landscape of plant genetic engineering, linking enabling platforms with trait‐focused applications in architecture optimization, stress resilience, yield improvement, and quality enhancement. It highlights how genome editing, transgenic strategies, and emerging multi‐gene approaches reshape breeding pipelines, while ...
Peilin Wang, Wenzhi Wang, Dongjiao Wang, Qibin Wu, Youxiong Que   +4 more
wiley   +1 more source

Research status quo of nutritional management of esophageal cancer patients during radiotherapy period

Huli yanjiu, 2020
This paper reviewed the research status quo of nutritional management of esophageal cancer patients during radiotherapy period.It aimed at providing reference for exploring the individualized nutritional management plan of esophageal cancer patients ...
WANG Peiru, WANG Yiru, ZHANG Jia, GUO Zhijun   +3 more
doaj  

Development and Management of Canine Adverse Food Reactions and its Connections to the Grain-Free Dog Food Movement [PDF]

, 2020
Canine Adverse Food Reactions include immunologically-mediated food allergies as well as non-immunological food intolerances. Although popular belief holds grains are responsible for AFR, the majority are aggravated by the common protein sources found in
Dunn, Savannah
core   +1 more source

Natural Variation of NAR5 Determines Nitrogenase Activity and the Yield in Soybean

Advanced Science, EarlyView.
This study identified NAR5, a gene encoding a subtilisin‐like protease, that regulates nitrogenase activity in soybean nodules. Overexpressing NAR5 delayed nodule senescence, enhancing nitrogenase activity, yield, and low‐nitrogen tolerance. The elite haplotype NAR5HapI‐1 linked to superior nitrogenase activity and greater seed weight has been ...
Chao Ma, Hanyu Zhao, Haojie Feng, Xulun Dong, Lin Chen, Mingliang Yang, Runyi Chen, Chengjun Lei, Chunyan Liu, Qingshan Chen, Dawei Xin, Jinhui Wang   +11 more
wiley   +1 more source

Dual‐Physical‐Field Nanocatalysis: Injectable Hydrogel Enables Piezo‐Photothermal Synergy for Breast Cancer Therapy

Advanced Science, EarlyView.
ABSTRACT Piezocatalytic therapy (PCT) harnesses mechanical energy to generate tumor‐lethal reactive oxygen species (ROS), but its efficacy is limited by rapid electron‐hole recombination and poor intratumoral retention. To overcome these limitations, we engineered heterostructured BiOCl@CuO nanosheets embedded in an injectable, conductive ...
Can Tian, Shihan Xiao, Xuan Chen, Danni Zhang, Zizhen Liu, Jing Wang, Ning Xie, Wei Li   +7 more
wiley   +1 more source

Application progress of artificial intelligence in nutritional management of chronic kidney disease

Huli yanjiu
This article briefly described the application status of artificial intelligence in dietary intake assessment,nutritional decision support,nutrition related risk prediction in chronic kidney disease.Additionally, the current application status of ...
YUAN Yi, ZHANG Hongmei, CHANG Liyang, TIAN Rongrong, LONG Zhiqiao   +4 more
doaj  

Oral Nutrition Supplements: Regulation and Distribution in Indonesia – a Study in a Private Hospital in Surabaya

Amerta Nutrition
Background: Oral Nutrition Supplements (ONS) in the Minister of Health Regulation No. 29 year 2019 which was made as the guidance of nutritional management for children with nutritional problems, especially growth failure (still prevalent) and became one
Lama'ah Azzahra', Nur Aisiyah Widjaja, Yasmine Nurfirdaus, Eva Ardianah, Edi Hermanto, Aziza Zahrotul Adha   +5 more
doaj   +1 more source

Hepatoma‐Derived Growth Factor Coordinates STAT3 Pathway and Exosome‐Mediated Intrahepatic Crosstalk to Control Hepatic Steatosis and MASLD

Advanced Science, EarlyView.
Hepatic HDGF as a key mediator in coordinating hepatic steatosis and intrahepatic crosstalk in MASLD. Activation of HDGF facilitates its interaction with both STAT3 and S6K1, driving the S6K1‐dependent STAT3 phosphorylation and subsequently enhancing hepatic lipogenesis.
Jian Wen, Dong Ding, Zengpeng Zheng, Xufeng Chen, Wenjing Li, Jiaxin Shen, Zhiwei Huang, Peng Tan, Junjie Bai, Xia Fang, Baofang Xing, Puyuan Hu, Linghao Xu, Haokai Yu, Yixi Wang, Zongzhe Jiang, Yang Long, Tiejun Zhou, Mingxin Ye, Yu Jiang, Aoyuan Cui, Hong Li, Qiurong Ding, Yong Xu, Yu Li, Weitong Su, Feng Shen, Chenlin Gao, Wenguang Fu   +28 more
wiley   +1 more source

Nutritional management of adult patients hospitalised with COVID-19 by dietitians in KwaZulu-Natal

The South African Journal of Clinical Nutrition
Background: The outbreak of a novel coronavirus disease (COVID-19) in December 2019 led to a worldwide pandemic. Dietitians treated patients hospitalised with COVID-19 without published guidelines on the nutritional management of the disease or prior ...
Kirthee Pillay, Naseera Ebrahim
doaj   +1 more source