Results 121 to 130 of about 9,379,117 (303)

Ahcy Acts as an Effector of Hnf4a‐Driven Super‐Enhancer Activation to Alleviate MASLD During Intermittent Fasting

Advanced Science, EarlyView.
Our study identifies an Hnf4a‐driven super‐enhancer of hepatic Ahcy that mediates the protective effects of intermittent fasting against MASLD. Disruption of the Ahcy super‐enhancer reduces Ahcy expression and exacerbates lipid accumulation. This pathway prevents aberrant promoter hypermethylation by maintaining the SAM/SAH balance, as exemplified by ...
Huafeng Chen, Shilin Zhang, Xiaojie Deng, Wenqiang Xie, Fen Xu, Jie Shen, Hua Liang   +6 more
wiley   +1 more source

Repository Strategic Management Business Journal

Strategic Management Business Journal is a forum for researchers in management science, especially in creating the effect of improving organizational performance in human resource management, financial management, and marketing management.
journal, strategic management business
core   +1 more source

Diet–vaccine interactions: SQM Iron and Salmonella vaccination shape poultry gut microbiota

Applied and Environmental Microbiology
Vaccines to prevent Salmonella are rapidly gaining traction in the poultry industry. Yet how these interventions interact with other management strategies to influence the broader gut microbial community, rather than Salmonella per se, remains poorly ...
Eldon O. Ager, Colette A. Nickodem, Jessica Brown, Joshua Jendza, Eric Neeno-Eckwall, Marisa Schuldes, Dana K. Dittoe, Jessica L. Hite   +7 more
doaj   +1 more source

GM‐CSF Promotes Neutrophil PD‐L1 Expression Through the VEGFR‐2/STAT6/CSF2 Signaling Axis in Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
VEGFR‐2 signaling in OSCC activates Src–STAT6‐dependent CSF2 transcription, driving tumor‐derived GM‐CSF secretion. GM‐CSF programs neutrophils to express PD‐L1 through STAT5–mTOR/S6K signaling, suppressing cytotoxic CD8+ T cells. This pathway reveals a tumor–neutrophil immune checkpoint circuit that limits anti‐PD‐1 responsiveness in OSCC.
Fangxing Zhu, Yuanhe You, Yiyi Zhang, Yibin Dai, Xinyu Zhou, Yong Fu, Xi Lu, Yingying Huang, Zhihang Zhou, Ronghui Xia, Wutong Ju, Zhaoqi Yuan, Laiping Zhong, Tongchao Zhao   +13 more
wiley   +1 more source

Nutritional Habits in Crohn’s Disease Onset and Management

Crohn’s disease (CD)’s activation factors are still unclear. However, they are reported to involve an interaction between genetic susceptibility and unhealthy lifestyle factors like smoking, alcohol consumption, low physical activity, low BMI
Georgia-Eirini Deligiannidou, Gavriela Voulgaridou, Sousana K. Papadopoulou, Konstantinos Papadimitriou, Constantinos Giaginis   +4 more
core   +1 more source

Improved assessment of child nutritional status using target weights and a novel, low-cost, weight-for-height slide chart.

, 2009
Correctly identifying malnourished or at-risk children is the critical first step towards appropriate nutritional interventions. To improve weight-for-height assessment and classification of nutritional status, we present a novel, low-cost, weight-for ...
Kerac, Marko, Bunn, James, Seal, Andrew, Blencowe, Hannah   +3 more
core   +1 more source

Asymmetric Evolution of Antennal Cell Types Underlies a Derived Ammonia‐Sensing Logic for Ecological Adaptation in Bactrocera dorsalis

Advanced Science, EarlyView.
Comparative antennal single‐nucleus transcriptomics reveals cell‐type‐dependent transcriptomic divergence in Bactrocera dorsalis, with similar structural cells but divergent sensory neurons. This neuronal diversification is associated with a distinct ammonia‐sensing pathway, linking female attraction to bird‐dropping‐associated cues with nutritional ...
Wei Liu, Shuai Zhang, Jie Zhang, Zhen Tian, Yuanbo Xue, Ling Yang, Jun Xu, Guirong Wang   +7 more
wiley   +1 more source

Nutritional Management for Crohn’s Disease

Nutrients
Diet has been implicated in the pathogenesis of inflammatory bowel disease (IBD) and, more specifically, Crohn’s disease (CD), for a long time [...]
Sara Sila, Iva Hojsak
openaire   +2 more sources

Drought Stress Mediated Changes in Food Crops: Mechanisms and Remediation Strategies

Advanced Science, EarlyView.
This work presents a multi‐scale framework for flavonoid‐mediated drought tolerance in staple food crops, integrating ROS redox regulation, antioxidant defense, rhizosphere microbial interactions, and sustainable agronomic practices. This interdisciplinary model provides core insights to develop climate‐resilient cropping systems and enhance global ...
Xiaoyi Duan, Litao Wang, Tuuli‐Marjaana Koski, Lizhe An, Thomas Efferth, Yujie Fu   +5 more
wiley   +1 more source

Nutritional management strategies post-liver transplantation: a comparative review of pediatric and adult recipients

Frontiers in Nutrition
Postoperative malnutrition occurs in 30–60% of liver transplant recipients and impairs perioperative recovery and long-term survival. Distinct malnutrition phenotypes exist across age groups, adult recipients mainly develop sarcopenia driven by sustained
Man Wang, Wei Gao, Zhixin Zhang, Meimei Si, Xiangyun Li, Qianyu Wang, Kexin Zhao, Ying Jiang   +7 more
doaj   +1 more source