Results 41 to 50 of about 9,379,117 (303)

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

First Fresheners: Getting Your Dairy Employees Off to a Good Start [PDF]

, 2017
The topics of this presentation, which was given on February 15th during the 71st Annual Convention : 2017 Virginia State Feed Association & Nutritional Management “Cow” College, include the importance of job analysis and descriptions, recruitment and ...
O'Rourke, Melissa
core  

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Nutritional support management in resectable gastric cancer

, 2022
Gastric cancer is the sixth most common malignancy in the world. However, its mortality has been decreasing in the last years thanks to improvement in diagnostics and therapeutics.
Viganò, Jacopo, Carminati, Ornella, Pedrazzoli, Paolo, Jacopo Viganò, Caccialanza R., Ornella Carminati, Pedrazzoli P, Corallo S., Brugnatelli, Silvia, Serra, Francesco, Pagani, Anna, Vigano J., Rosti G., Corallo, Salvatore, Pagani A., Riccardo Caccialanza, Carminati O, Salvatore Corallo, Paolo Pedrazzoli, Rosti G, Pedrazzoli P., Serra F., Anna Pagani, Caccialanza, Riccardo, Serra F, Pagani A, Rosti, Giovanni, Viganò J, Giovanni Rosti, Brugnatelli S, Carminati O., Francesco Serra, Corallo S, Brugnatelli S., Silvia Brugnatelli, Caccialanza R   +35 more
core   +1 more source

A Low Psoas Muscle Index Was Associated With a Poorer Overall Survival in Patients Who Underwent Percutaneous Nephrostomy

Aging and Cancer, EarlyView.
In patients with malignant ureteral obstruction undergoing percutaneous nephrostomy, sarcopenia defined by a low psoas muscle index was independently associated with poor overall survival on multivariate Cox regression analysis, suggesting that preoperative assessment of psoas muscle index may aid prognostic stratification in this population.
Kota Shimokihara, Takashi Kawahara, Kazuhide Makiyama, Hiroji Uemura   +3 more
wiley   +1 more source

Economic Challenges in Nutritional Management [PDF]

Journal of Clinical Medicine, 2019
Disease-related malnutrition (DRM) is a highly prevalent independent risk and cost factor with significant influence on mortality, morbidity, length of hospital stay (LOS), functional impairment and quality of life. The aim of our research was to estimate the economic impact of the introduction of routinely performed nutritional screening (NS) in a ...
Emilie Reber, Kristina Norman, Olga Endrich, Philipp Schuetz, Andreas Frei, Zeno Stanga   +5 more
openaire   +3 more sources

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

Aging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi, Emily Herdman, Danielle Westmark, Vijaya R. Bhatt   +3 more
wiley   +1 more source

Nutritional Guideline for the Management of Mexican Patients with CKD and Hyperphosphatemia

, 2020
Chronic kidney disease (CKD) represents a serious concern for the Mexican population since the main predisposing diseases (diabetes, hypertension, etc.) have a high prevalence in the country.
Laura M. Islas Romero, Olinto A. Luna-Montiel, Daniela L. Guillen-Tejada, Taísa S. Silva Pereira, Ana E. Ortega-Régules, Frida Palafox-Serdán, Aura M. Jiménez-Garduño, Sebastián E. Pablo-Franco, Sandra D. Carreño-Vázquez, Karen Villaseñor López   +9 more
core   +1 more source