Principles for Rigorous Design and Application of Synthetic Microbial Communities
SynComs are artificially designed to enable inter‐species metabolic interactions, metabolic division of labor, and ecological interactions that can elicit phenotypes like colonization stability and environmental adaptation. This systematic review explores the processes used to construct SynComs, the assessment of the mechanisms of metabolic interaction
Yuxiao Zhang +21 more
wiley +1 more source
The human metabolome under nutritional challenges in young men and subjects carrying risk alleles for obesity and diabetes mellitus type 2 [PDF]
Susanne M. Krug
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Elevated Plasma Vitamin B12 Concentrations Are Independent Predictors of In-Hospital Mortality in Adult Patients at Nutritional Risk [PDF]
Silvia Cappello +9 more
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Meta‐GWAS of Pig Semen Quality Traits Reveals Conserved Genes Regulating Mammalian Fertility
This study incorporated 14 210 individuals to perform a GWAS meta‐analysis of six semen quality traits. The GWAS meta‐analysis identifies 234 GWAS loci associated with semen quality traits. The incorporation with a functional genomics resource explains potential genetic regulation of ∼40% GWAS signals underlying semen quality traits.
Qing Lin +26 more
wiley +1 more source
Measuring Nutrition Status, Physical Activity, and Fitness, with Special Emphasis on Populations at Nutritional Risk [PDF]
Victor Keihan Rodrigues Matsudo
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Connexin43 Deficiency Leads to Ventricular Arrhythmias by Reprogramming Proline Metabolism
The study demonstrated that connexin43 (Cx43) knockout caused arrhythmic phenotype and decreased proline content in vitro and in vivo. Mechanistically, Cx43 interacts with the amino acid transporter SNAT2 (sodium‐dependent neutral amino acid transporter), and its deficiency disrupts proline transport and metabolism.
Hangying Ying +8 more
wiley +1 more source
SAT0609 WOMEN WITH METABOLIC SYNDROME AND GENERAL OBESITY ARE AT HIGHER RISK FOR SIGNIFICANT HYPERURICEMIA THAN MEN: RESULTS FROM THE 2016 KOREA NATIONAL HEALTH AND NUTRITION EXAMINATION SURVEY [PDF]
Yeonghee Eun +8 more
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The relationship between systemic inflammation, body composition and clinical outcomes in patients with operable colorectal cancer at low and medium to high nutritional risk [PDF]
Tanvir Abbass +3 more
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The Regulatory Role of Iron Transporter SLC39A13 in Liver Fibrosis
SLC39A13/ZIP13, a newly discovered intracellular iron transporter, delivers iron to the ER/Golgi to catalyze procollagen hydroxylation during collagen maturation. Here, we systematically characterize the cell type‐specific functions of ZIP13 across distinct hepatic cell populations, and identify hepatic stellate cell‐specific ZIP13 as a promising and ...
Shanshan Guo +5 more
wiley +1 more source
Prognostic value of geriatric nutritional risk index in patients with amyotrophic lateral sclerosis [PDF]
Wenxiu Yu +6 more
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