Results 131 to 140 of about 490,382 (266)

The RNA‐Binding Protein PARN Remodeled 3′ UTR Structure Defines Poly(A)‐Loading Sites to Mediate Immunoglobulin Homeostasis

open access: yesAdvanced Science, EarlyView.
ABSTRACT Class Switch Recombination (CSR) is essential for generating high‐affinity antibody isotypes from IgM during adaptive humoral responses. Despite well‐established roles for various transcription factors, whether CSR is subject to dedicated post‐transcriptional control represents a significant gap in knowledge.
Siyuan Sun   +19 more
wiley   +1 more source

Stage‐Specific H3K14 and H3K23 Succinylation Orchestrates Insect Metamorphosis and Oogenesis

open access: yesAdvanced Science, EarlyView.
Stage‐specific succinylation of histone H3 at lysine 14 and 23 differentially controls insect metamorphosis and oogenesis through distinct GPCR‐PKC signaling cascades, revealing an evolutionarily conserved epigenetic mechanism that coordinates key life‐history traits.
Yu‐Pu Jing   +9 more
wiley   +1 more source

T‐Cell Exhaustion in the Tumor Microenvironment: Subcellular Dysfunction, Pan‐Cancer Characteristics, and Therapeutic Interventions

open access: yesAdvanced Science, EarlyView.
This study elucidates the mechanisms of subcellular multidimensional collapse in exhausted T cells. By specifically targeting the nucleus, mitochondria, and endoplasmic reticulum, strategic interventions can effectively remodel the compromised organelle network. This integrated approach drives comprehensive T cell resuscitation, ultimately establishing
Mingxing Wang   +9 more
wiley   +1 more source

Questionnaires for Evaluation the Nutritional Status of Cancer Patients

open access: yesApplied Medical Informatics
The evaluation of the nutritional status of the cancer patient is necessary during the oncological follow-up. The use of assessment tools becomes reliable in the nutritional status of these patients, providing accurate information on the patient's ...
Claudia Raluca BALASA VIRZOB   +2 more
doaj  

Trophic Diversity in Duckweed: Mixotrophy, More Than the Sum of its Extremes

open access: yesAdvanced Science, EarlyView.
In the context of rising DOC in aquatic environments, mixotrophic duckweed may impact carbon cycling by acting as either a carbon sink, as they absorb CO2 through photosynthesis, or a carbon source, as they release CO2 through respiration of absorbed DOC, which depends on DOC concentration, light availability, temperature, and other environmental ...
Zuoliang Sun   +5 more
wiley   +1 more source

Perfil antropométrico de funcionários de banco estatal no Estado do Rio de Janeiro/Brasil: I índice de massa corporal e fatores sócio-demográficos

open access: yesCadernos de Saúde Pública
Estudo seccional que objetivou descrever o perfil antropométrico de funcionários do Banco do Brasil e compará-lo aos resultados da Pesquisa Nacional Sobre Saúde e Nutrição PNSN/1989 para a região Sudeste. Utilizou-se uma amostra de 647 bancários.
Erica Ell   +2 more
doaj  

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