Results 111 to 120 of about 537,194 (266)

Unveiling Lactylation: A Novel Frontier in Cancer Stemness and Therapy

Advanced Science, EarlyView.
Tumor metabolism and epigenetic regulation are intrinsically linked. This review highlights lactylation as a pivotal bridge connecting these processes, acting as an active epigenetic effector in cancer stemness. We delineate how lactylation orchestrates the cancer stem cell landscape and evaluate its regulatory networks.
Ting Li, Hongyu Gu, Chang Liu, Yuesheng Lv, Feifei Li, Liang Liang, Jia Yi, Xuanyi Wang, Yi Zhun Zhu, Chuan Xu   +9 more
wiley   +1 more source

Predicting Morbidity in Pancreaticoduodenectomy: A Focus on Nutritional Status. [PDF]

Cureus
Ali S, Bhat MY, Lattoo MR, Sohi AS, Vane A.   +4 more
europepmc   +1 more source

Stress History Establishes a Transient Tolerant State That Shapes Antibiotic Survival Upon Resuscitation

Advanced Science, EarlyView.
High‐throughput single‐cell analysis of resuscitating bacteria reveals a starvation‐history‐dependent transiently tolerant subpopulation that survives β$\beta$‐lactam exposure by temporarily reducing growth. Distinct from classical persisters, these actively growing yet dynamically modulated cells dominate survival across clinically relevant antibiotic
Kieran Abbott, Georgeos Hardo, Ruizhe Li, Jack Bradley, Ashraf Zarkan, Somenath Bakshi   +5 more
wiley   +1 more source

Nutritional Status as a Severity Predictor in Critical Pediatric Patients With COVID-19. [PDF]

Pediatr Pulmonol
Andrades GRH, Rodrigues-Santos G, Robaina JR, de Oliveira MBG, Salú MDS, Lima FC, Cunha AJLAD, Barbosa MCM, Prata-Barbosa A, Costa CAD.   +9 more
europepmc   +1 more source

Integrative Multi‐Omics Analysis Reveals a Mitochondrial–Immune Axis Associated With Neoadjuvant Chemotherapy Response in High‐Grade Serous Ovarian Cancer

Advanced Science, EarlyView.
Integrative multi‐omics analysis delineates a mitochondrial–immune axis governing neoadjuvant chemotherapy response in high‐grade serous ovarian cancer. Immune‐active tumors exhibit enhanced B‐cell infiltration and favorable sensitivity, whereas metabolically rewired tumors display oxidative phosphorylation dependency and resistance.
Wei Jiang, Yi Wang, Xiaohang Lu, Qianlan Yao, Libing Xiang, Xu Cai, Xiaoyu Tu, Shaoxian Tang, Ying Xu, Yufan Cheng, Liming Shen, Huijuan Yang   +11 more
wiley   +1 more source

Nutritional Status and Physical Activity Levels in Adult Patients with Phenylketonuria. [PDF]

Nutrients
Kalkan D, Yıldız Y, Karanfil Y, Korkusuz F, Dursun A, Sivri S, Gökmen Özel H.   +6 more
europepmc   +1 more source

Human‐Centered Innovation: Precision Nutrition and the Future of Food

Advanced Science, EarlyView.
ABSTRACT Nutritional science is moving beyond one‐size‐fits‐all recommendations toward more precise and personalized approaches, yet its implementation pathway remains unclear. This paper proposes a human‐centered precision nutrition framework that highlights the central roles of artificial intelligence (AI), food innovation, and human agency.
Shanshan Zhang, Yonggan Sun, Jiaqi Jiang, Shaoping Nie   +3 more
wiley   +1 more source

Why we should be worried about the future of nutrition

Social Determinants of Health, 2023
Sushmitha Mahantshetti, Srihari Dhandapani, Gowthamkarthic, Sandhya Gowthaman, Soumya Agadi   +4 more
doaj   +1 more source

Prognostic Impact of Nutritional Status in Patients with Candidemia. [PDF]

Nutrients
Asai N, Ohashi W, Shibata Y, Sakanashi D, Kato H, Hagihara M, Mikamo H.   +6 more
europepmc   +1 more source

Gut Microbiota, Immunity, and Metabolism in the Progression From Chronic Liver Disease to Hepatocellular Carcinoma

Advanced Science, EarlyView.
This review explains how chronic liver injury progresses toward hepatocellular carcinoma through interconnected changes in gut microbes, metabolism, immunity, fibrosis, and diet. It highlights microbial metabolites, bile‐acid signaling, immune dysfunction, and nutritional or microbiome‐based interventions as opportunities to identify risk earlier ...
Yi Hu, Caiyan Lin, Lijie Zhang, Xue Jiang, Huawen Li, Yangzhe Wu   +5 more
wiley   +1 more source