Results 81 to 90 of about 8,953,666 (341)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

How sustainable are hypocaloric and balanced diets for weight loss?

Nutrition & Metabolism
Background Promoting healthy diets with low environmental impact is pivotal. The EAT-IT diet aligns with the EAT-Lancet Commission, tailored to Italian food habits. However, a comparison with weight loss diets has not been done.
Ramona De Amicis, Andrea Foppiani, Alessandro Leone, Federica Sileo, Francesca Menichetti, Sara Paola Mambrini, Marta Pellizzari, Massimiliano Tucci, Daniela Martini, Cristian Del Bo, Patrizia Riso, Simona Bertoli, Alberto Battezzati   +12 more
doaj   +1 more source

Evaluation of food consumption, energy availability and adherence to the Mediterranean dietary pattern in a group of non-professional athletes

Frontiers in Nutrition
Background and aimAdequate nutritional intake is fundamental for optimizing athletic performance and maintaining health. The aim of the present study was to investigate the dietary habits of a group of non-professional athletes, assessing their capacity ...
Ellis Bianchi, Massimiliano Tucci, Simone Perna, Daniela Martini, Cristian Del Bo', Cristian Del Bo', Alessandro Leone, Alessandro Leone, Francesca Menichetti, Simona Bertoli, Simona Bertoli, Alberto Battezzati, Alberto Battezzati, Patrizia Riso, Patrizia Riso   +14 more
doaj   +1 more source

Is nutritional status associated with the level of anxiety, depression and pain in patients with lung cancer?

Journal of Thoracic Disease, 2018
Background Nutritional deficiencies are common in lung cancer patients, especially in those with advanced and metastatic cancers. The pathogenesis of the development of nutritional disorders in cancer patients has not been fully explained.
M. Chabowski, J. Polański, B. Jankowska-Polańska, D. Janczak, J. Rosińćzuk   +4 more
semanticscholar   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Abnormal fatty acid metabolism is a core component of spinal muscular atrophy

Annals of Clinical and Translational Neurology, 2019
Objective Spinal muscular atrophy (SMA) is an inherited neuromuscular disorder leading to paralysis and subsequent death in young children. Initially considered a motor neuron disease, extra‐neuronal involvement is increasingly recognized.
Marc‐Olivier Deguise, Giovanni Baranello, Chiara Mastella, Ariane Beauvais, Jean Michaud, Alessandro Leone, Ramona De Amicis, Alberto Battezzati, Christopher Dunham, Kathryn Selby, Jodi Warman Chardon, Hugh J. McMillan, Yu‐Ting Huang, Natalie L. Courtney, Alannah J. Mole, Sabrina Kubinski, Peter Claus, Lyndsay M. Murray, Melissa Bowerman, Thomas H. Gillingwater, Simona Bertoli, Simon H. Parson, Rashmi Kothary   +22 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Bioelectrical impedance in the assessment of nutritional status

Journal of Education, Health and Sport, 2020
IntroductionBioelectrical impedance analysis is based on the difference in electric conduction in the water and fat environment. Adipose tissue and extracellular water are devoid of capacitive resistance (reactance), whereas they show passive electrical ...
Patrycja Ręba
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source