Spatiotemporal Multi‐Omic Mapping Reveals Liver‐Muscle Metabolic Crosstalk in Cancer Cachexia
The interactive CCAtlas platform delineates cross‐species, spatiotemporal, and sex‐specific molecular dynamics and metabolic rewiring across organs during cancer cachexia. Hepatic Gamt downregulation curtails hepatic creatine synthesis to trigger systemic creatine insufficiency and consequent skeletal muscle atrophy in LLC tumour‐bearing mice ...
Zihan Tian +12 more
wiley +1 more source
Nutrition Support by the Enteral Nutrition
openaire +2 more sources
Optimizing Nutritional Support Through the Retromolar Space. [PDF]
Yadav S +4 more
europepmc +1 more source
Water‐soluble amine‐functionalized polyhedral oligomeric silsesquioxane promotes concurrent latex coalescence and crosslinking, allowing epoxy‐functional particles to form continuous films without added volatile coalescing agents. The resulting multiscale‐reinforced waterborne coatings combine high strength, toughness, optical transparency, scratch ...
Chao Wang +7 more
wiley +1 more source
Individual Amino Acid Supplementation Does Not Enhance Short-Term Proliferation of Selected Cancer Cell Lines In Vitro: Potential Implications for Nutritional Support in Cancer Cachexia. [PDF]
Dieterich W +5 more
europepmc +1 more source
A tumor‐state‐gated metallo‐DNAzyme framework integrates miR‐21/APE1‐responsive GLUT1 silencing with Ca/Cu‐partitioned metal–nucleic acid assembly and cystine loading. The framework first weakens glucose‐dependent metabolic buffering and then amplifies copper‐ and disulfide‐associated stress, converting tumor metabolic adaptation into programmable ...
Xiaodong Ma +8 more
wiley +1 more source
High Prevalence of Malnutrition and Sarcopenia with Inadequate Nutritional Support in Intensive Care Unit Patients: A Prospective Observational Study of Clinical Outcomes. [PDF]
Ben Othman R +8 more
europepmc +1 more source
Mesenchymal GSCs preferentially uptake palmitic acid, thereby promoting ZDHHC12‐mediated LDHA palmitoylation. This modification enhances LDHA enzymatic activity, drives glycolytic reprogramming, and facilitates exosomal LDHA‐mediated TAM regulation.
Zijie Gao +20 more
wiley +1 more source
Preoperative nutritional support in children with Hirschsprung disease: a prospective multicenter open-label randomized controlled trial. [PDF]
Zhang HY +14 more
europepmc +1 more source
Tumor Exposomics: A New Paradigm for Individualized Continuous Exposure Monitoring
Tumor exposomics integrates continuous monitoring of environmental exposures, endogenous biological responses, and behavioral factors within a unified temporal framework. By combining multimodal sensing technologies with AI‐enabled causal modeling, this emerging paradigm reconstructs exposure‐damage trajectories and supports individualized dynamic risk
Kaicheng Shen +6 more
wiley +1 more source

