Results 101 to 110 of about 18,311 (291)

Functional Analysis of Ligand‐Gated Chloride Channels in a Cnidarian Sheds Light on the Evolution of Inhibitory Signaling

Advanced Science, EarlyView.
We uncover a large variety of putative inhibitory ligand‐gated ion channels (LGICs) in the phylum Cnidaria, the sister group to all bilaterian animals. Phylogenetic analysis suggests a complex evolutionary history of inhibitory LGICs with diverse neurotransmitter ligands.
Abhilasha Ojha, Linda Kloss, Juan D. Montenegro, Simone Albani, Audrey Ortega‐Ramírez, Mihaela Raycheva, Sylvia Joussen, Sabrina Kaul, Michèle Bachmann, Lisa Huf, Günther Schmalzing, Alison G. Cole, Ulrich Technau, Stefan Gründer   +13 more
wiley   +1 more source

Helix Alignment, Chevrons, and Edge Dislocations in Twist‐Bend Ferroelectric Nematics

Advanced Science, EarlyView.
The recently discovered twist‐bend ferroelectric nematic (NTBF) is the new member of the multiferroic family, representing a fluid with an oblique helicoidal (heliconical) periodic structure of spontaneous electric polarization. The work presents a thorough exploration of the material properties of this phase, how the periodic modulation of ...
Bijaya Basnet, Priyanka Kumari, Sathyanarayana Paladugu, Damian Pociecha, Jakub Karcz, Przemysław Kula, Nataša Vaupotič, Ewa Górecka, Oleg D Lavrentovich   +8 more
wiley   +1 more source

Identification and Reversible Optical Switching of NV⁺ Centers in Diamond

Positive nitrogen-vacancy centers (NV+) in diamond are predicted to exist in conjunction with neutral (NV0) and negative (NV−) centers. However, the existence of NV+ has only been indirectly inferred through a shift of the Fermi level.
Mathes, Lucian, Liedke, Maciej Oskar, Hugenschmidt, C., Dollinger, G., Butterling, M., Liedke, M., Sperr, Peter, Dickmann, Marcel, Dollinger, Günther, Burwitz, V., Schwarz-Selinger, T. ; https://orcid.org/, Egger, W., Mitteneder, Johannes, Wagner, A., Hugenschmidt, Christoph, Dickmann, M., Helm, R., Mitteneder, J., Burwitz, Vassily Vadimovitch, Dorner, Joachim, Egger, Werner, Helm, Ricardo, Mathes, L., Wagner, Andreas, Sperr, P., Schwarz-Selinger, Thomas, Dorner, J., Butterling, Maik   +27 more
core   +1 more source

The AUTACE That Degrades KRAS and Engages CD8+ T Cells for the Treatment of KRAS/TP53 Co‐Mutant Tumors

Advanced Science, EarlyView.
AUTACE is a bifunctional nanoplatform that integrates tumor targeting, immune engagement, and on‐demand KRAS degradation. It targets KRAS/TP53 co‐mutant tumors via TP53‐specific TCRs, elicits antitumor CD8+ T‐cell responses through surface anti‐CD3 antibodies, and uses low‐intensity focused ultrasound (LIFU) to trigger controlled release of the KRAS ...
Luo Li, Bolin Li, Yanan Hao, Bo Pang, Pan Li, Chunli Li, Yu Tang   +6 more
wiley   +1 more source

Infrared laser threshold magnetometry using diamond NV centers

, 2020
International audienceWe theoretically study a hybrid laser magnetometer cavity combining a semiconductor medium to obtain the optical gain and a diamond etalon containing nitrogen vacancy (NV) colored centers as magnetic field probe.
Budker, Dmitry, Debuisschert, Thierry, Chatzidrosos, Georgios, Wickenbrock, Arne, Becher, Christoph, Roch, Jean-François, Acosta, Victor, Bretenaker, Fabien, Dumeige, Yannick, Wilzewski, Alexander, Bougas, Lykourgos   +10 more
core  

ESCRT‐Mimetic Nanodegrader Targets STING for Anti‐Inflammatory Therapy

Advanced Science, EarlyView.
A nanoplatform‐enabled targeted protein degradation strategy is presented to regulate aberrant STING signaling. STING‐ATTEC induces selective autophagic degradation of STING via formation of a STING–ATTEC–LC3 ternary complex, while the cationic FA‐LNP+ system enhances LC3 generation and targeted delivery. Together, this synergistic approach efficiently
Fuyuan Zhou, Qiming Zhai, Zhihao Yao, Qing Li, Yan Yang, Si Wang, Chao Huang, Liangjing Xin, Tao Chen, Jinlin Song   +9 more
wiley   +1 more source

A review of the study of diamond NV color centers: fabrication, application and challenge

Functional Diamond
Nitrogen-vacancy (NV) color centers in diamond have emerged as a focal point in quantum technology research due to their exceptional optical and electronic spin properties.
Yunyun Li, Han Li, Tao Yi, Chengming Li, Junjun Wei   +4 more
doaj   +1 more source

Origins of Diamond Surface Noise Probed by Correlating Single-Spin Measurements with Surface Spectroscopy

Physical Review X, 2019
The nitrogen-vacancy (NV) center in diamond exhibits spin-dependent fluorescence and long spin coherence times under ambient conditions, enabling applications in quantum information processing and sensing.
Sorawis Sangtawesin, Bo L. Dwyer, Srikanth Srinivasan, James J. Allred, Lila V. H. Rodgers, Kristiaan De Greve, Alastair Stacey, Nikolai Dontschuk, Kane M. O’Donnell, Di Hu, D. Andrew Evans, Cherno Jaye, Daniel A. Fischer, Matthew L. Markham, Daniel J. Twitchen, Hongkun Park, Mikhail D. Lukin, Nathalie P. de Leon   +17 more
doaj   +1 more source

Reinnervation of Muscle Targets Enhances the Separability of Motor Unit Signals Following Peripheral Nerve Transfers

Advanced Science, EarlyView.
Injured or cut peripheral nerves can be surgically rerouted to reinnervate new muscle targets. This study demonstrates reinnervated muscles exhibit enhanced separability between individual motor unit signals, which can simplify signal recording and decomposition. These findings highlight the potential of reinnervated muscle to serve as a key biological
Kiara N Quinn, Siyu Wang, Lang Qin, Alessandro Ascani Orsini, Kenzi Griffith, Rachana Suresh, Fausto Kang, Pierce L Perkins, Neha Joshi, Alexis L Lowe, Sami Tuffaha, Nitish V Thakor   +11 more
wiley   +1 more source

Understanding surface-induced decoherence of NV centers in diamond

Physical Review Materials
Nitrogen vacancy centers (NV) in proximity to diamond surfaces are promising nanoscale quantum sensors. However, their coherence properties are negatively affected by magnetic and electric surface noise, whose origin and detailed impact have remained elusive.
Jonah Nagura, Mykyta Onizhuk, Giulia Galli   +2 more
openaire   +2 more sources