Results 41 to 50 of about 10,687 (160)

Utilization of immune checkpoint inhibitors for the treatment of cancer in Scotland, 2018–2024: A national retrospective cohort study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims The aim of the study is to describe the use of immune checkpoint inhibitors (ICIs) for the treatment of cancer in Scotland. Methods The retrospective observational cohort study included patients aged 18 years or older who commenced treatment with an ICI in Scotland between 1 January 2018 and 31 December 2024.
Tanja Mueller   +9 more
wiley   +1 more source

Global Energy Corporations and Climate Change: The Role of Formal and Informal Institutions in Shaping Climate Change Risk Disclosure

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT This study examines climate change risk disclosure in the global energy sector, where firms face intense stakeholder scrutiny and legitimacy pressures. We develop a novel domain‐specific textual analysis measure to capture climate change risk disclosures, improving on prior approaches based on generic environmental terminology.
Khaldoon Albitar, Ali Meftah Gerged
wiley   +1 more source

Highly Potent Fluorogenic Ligands for Triplex DNA: 5‐Substituted 2‐(Naphthalen‐2‐yl)‐4H‐Chromen‐4‐Ones

open access: yesChemistry – A European Journal, EarlyView.
5‐Substituted 2‐(naphthalen‐2‐yl)‐4H‐chromen‐4‐ones are reported as a novel class of highly potent and selective triplex DNA ligands. These ligands induce triplex formation at submicromolar concentrations and inhibit enzymatic activity via ligand‐mediated triplex formation.
Nghia Tran   +4 more
wiley   +1 more source

A Análise de Redes Sociais no estudo do processo da construção da ajuda mútua da pessoa com doença oncológica com blogue

open access: yesREDES: Revista Hispana para el Análisis de Redes Sociales, 2014
Os recentes desenvolvimentos na saúde, sociedade e tecnologia, têm conduzido a novas formas de estar. Encarar hoje a doença oncológica (DO) é enfrentar um desafio. A comunicação, também sofreu evolução e a Internet assume um espaço crescente na sociedade.
Carla Piscarreta Damásio   +2 more
doaj   +1 more source

Electrical resistance tomography for process intensification of gas–liquid stirred tanks: A comparison of linear back projection and sensitivity conjugate gradient algorithms

open access: yesThe Canadian Journal of Chemical Engineering, EarlyView.
Monitoring gas–liquid dynamics using Electrical resistance tomography for process intensification in stirred tanks Abstract Electrical resistance tomography (ERT) is a non‐invasive technique widely applied to the study of multiphase flows, where phases exhibit different electrical properties.
Federico Alberini   +2 more
wiley   +1 more source

Novel Zwitterionic Polydopamine Nanofiller‐Reinforced Hybrid Membranes With Superior Antifouling Performance for Wastewater Treatment

open access: yesENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
This work reports one‐pot synthesized novel zwitterionic polydopamine‐silica (ZSiPDA) nanofillers for fabricating PES hybrid ultrafiltration membranes with enhanced hydrophilicity, permeability, and antifouling performance. The optimized membrane achieved over 91% humic acid removal and showed strong potential for municipal wastewater treatment.
Roqaya A. Ismail   +5 more
wiley   +1 more source

Prolonged fenfluramine use in open‐label studies of Dravet or Lennox–Gastaut syndromes: Long‐term safety, tolerability, patient global functioning, and considerations for interpreting effectiveness

open access: yesEpilepsia, EarlyView.
This graphical abstract provides an overview of the content from this open‐label extension study of fenfluramine use in patients with Dravet syndrome or Lennox‐Gastaut syndrome. Abstract Objective Long‐term safety and global functioning are reported in patients with Dravet syndrome (DS) or Lennox–Gastaut syndrome (LGS) treated with fenfluramine in an ...
Antonio Gil‐Nagel   +18 more
wiley   +1 more source

Apetites e excreções em Blurt, Major Constable, or The Spaniard’s Night Walk de Thomas Dekker

open access: yesActa Scientiarum: Language and Culture, 2018
O presente ensaio oferece uma análise de Blurt, Major Constable, or The Spaniard’s Night Walk (1601–1602) de Thomas Dekker, com enfoque na construção do nexo comida-bebida-sexo-excrementos no texto.
Ana Cristina Mendes
doaj   +1 more source

Experimental and Numerical Investigation of Cedar Façade Flame Spread With Respect to Sidewall

open access: yesFire and Materials, EarlyView.
ABSTRACT In response to growing energy conservation and carbon neutrality efforts, façade systems incorporating wooden materials have attracted increasing attention, which in turn raises concerns about their combustibility. This study presents a combined experimental and numerical investigation of flame spread along cedar façades.
Xukun Sun   +6 more
wiley   +1 more source

Assessing the Performance of the Copernicus European Regional Reanalysis Dataset in Reproducing Extreme Weather Events in Poland

open access: yesInternational Journal of Climatology, EarlyView.
Global reanalyses, for example ERA5 and ERA5‐Land, tend to misrepresent the local‐scale weather extremes due to the limited spatial resolution. In this paper CERRA shows clear and consistent improvements over ERA5 and ERA5‐Land in representing extreme temperature and precipitation in Poland, particularly for localized and short‐lived heavy rainfall ...
Kinga Kulesza   +2 more
wiley   +1 more source

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