Results 241 to 250 of about 16,307,918 (298)

Attomolar Detection of HIV‐1 With Label‐Free RCA‐rCRISPR on Smartphone

Advanced Science, EarlyView.
A new diagnostic strategy integrating rolling circle amplification (RCA) with a plasmid reporter–based ratiometric CRISPR (rCRISPR) system was developed to detect unfragmented HIV genomes with single‐digit attomolar sensitivity. The method quantifies targets using the plasmid relaxation ratio and employs a smartphone‐based mini‐gel device to enable ...
Noor Mohammad, Anastasiia Steksova, Yuyang Tang, Leyao Huang, Alireza Velayati, Shengwei Zhang, Aditi Dey Poonam, Sina Jamalzadegan, Matthew Breen, Hongjie Chen, Mahsa Bagi, Guochun Jiang, Qingshan Wei   +12 more
wiley   +1 more source

TRAIP Mediates Alcohol‐Induced Liver Injury through Regulating β‐catenin Ubiquitin Degradation via Direct Interaction

Advanced Science, EarlyView.
This study reveals that NF‐κB1‐driven TRAIP upregulation in ALD correlates with disease severity. Mechanistically, TRAIP directly binds β‐catenin via its CC domain and promotes its K48‐linked ubiquitination and degradation, which is independent of the GSK3β/β‐TrCP pathway.
Zhan Wu, Mingjiang Liu, Lijuan Liao, Zhaohong Mo, Wenli Xu, Linfeng Mao, Yubing Chen, Qiuli Xie, Ming Yao, Shilian Chen, Stephen Tomlinson, Sebastian Mueller, Songqing He, Guandou Yuan   +13 more
wiley   +1 more source

Preclinical validation of an <i>Escherichia coli</i> O-antigen glycoconjugate for the prevention of serotype O1 invasive disease. [PDF]

Microbiol Spectr
Chorro L, Ndreu D, Patel A, Kodali S, Li Z, Keeney D, Dutta K, Sasmal A, Illenberger A, Torres CL, Pan R, Silmon de Monerri NC, Chu L, Simon R, Anderson AS, Donald RGK.   +15 more
europepmc   +1 more source

Mapping the architecture of the initiating phosphoglycosyl transferase from S. enterica O-antigen biosynthesis in a liponanoparticle. [PDF]

Elife
Dodge GJ, Anderson AJ, He Y, Liu W, Viner R, Imperiali B.   +5 more
europepmc   +1 more source

High diversity ofEscherichia colicausing invasive disease in neonates in Malawi poses challenges for O-antigen based vaccine approach

Pearse O, Zuza A, Tewesa E, Siyabuh P, Fraser AJ, Cornick J, Kawaza K, Musicha P, Thomson NR, Feasey NA, Heinz E.   +10 more
europepmc   +1 more source

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The lipopolysaccharides (O-antigens) of Rhodopseudomonas viridis

Archives of Microbiology, 1974
The present paper deals with the isolation, and chemical and serological characterization of the O-antigens (lipopolysaccharides, LPS) of the photosynthetic gram-negative bacterium Rhodopseudomonas viridis. The LPS are extractable with hot phenol/water, but unlike the phenol-soluble LPS of the closely related species Rhodopseudomonas palustris, the R ...
J, Weckesser, G, Drews, J, Roppel, H, Mayer, I, Fromme   +4 more
openaire   +2 more sources

Identification of Salmonella O antigens by coagglutination

Journal of Clinical Microbiology, 1984
This study concerns the preparation of reagents for identifying the somatic O antigens of Salmonella enteritidis. Coagglutination reagents (COAGs) with antibody fixed to killed and stabilized protein A-bearing staphylococci were prepared with antisera which were used for identifying the somatic O antigens of S.
J O, Cohen, L E, Britt, W K, Harrell
openaire   +2 more sources

Immunochemistry of Salmonella O-Antigens

International Archives of Allergy and Applied Immunology, 2009
The binding specificities of antibodies directed against the Salmonella sero-group A-specific O-antigen 2 determinant were characterized by precipitation-inhibition and enzyme-linked immunosorbent assay inhibition tests. Two different antigen O-2-specific antisera were investigated: one conventional factor O-2-serum (elicited by whole heat-killed ...
H. Jörbeck, S.B. Svenson, A.A. Lindberg
openaire   +2 more sources

The O-antigen of Salmonella enterica O13 and its relation to the O-antigen of Escherichia coli O127

Carbohydrate Research, 2010
The following structure of the O-polysaccharide (O-antigen) of Salmonella enterica O13 was established by chemical analyses along with 2D (1)H and (13)C NMR spectroscopy: -->2)-alpha-l-Fucp-(1-->2)-beta-d-Galp-(1-->3)-alpha-d-GalpNAc-(1-->3)-alpha-d-GlcpNAc-(1--> The O-antigen of S.
Andrei V, Perepelov, Bin, Liu, Sof'ya N, Senchenkova, Sergei D, Shevelev, Lu, Feng, Alexander S, Shashkov, Lei, Wang, Yuriy A, Knirel   +7 more
openaire   +2 more sources

Structural studies of the Vibrio cholerae o-antigen

Carbohydrate Research, 1979
The dominant part of the O-antigen of Vibrio cholerae is a homopolysaccharide composed of (1 leads to 2)-linked 4-amino-4,6-dideoxy-alpha-D-mannopyranosyl (perosaminyl) residues, in amino groups of which are acylated by 3-deoxy-L-glycero-tetronic acid. Most of the amino sugar is decomposed during acid hydrolysis. Treatment of the polymer with anhydrous
L, Kenne, B, Lindberg, P, Unger, T, Holme, J, Holmgren   +4 more
openaire   +3 more sources