Results 11 to 20 of about 123,332 (275)

o1-Coder: an o1 Replication for Coding

open access: yesCoRR
The technical report introduces O1-CODER, an attempt to replicate OpenAI's o1 model with a focus on coding tasks. It integrates reinforcement learning (RL) and Monte Carlo Tree Search (MCTS) to enhance the model's System-2 thinking capabilities. The framework includes training a Test Case Generator (TCG) for standardized code testing, using MCTS to ...
Yuxiang Zhang   +6 more
openaire   +4 more sources

OpenAI o1 System Card [PDF]

open access: yesCoRR
The o1 model series is trained with large-scale reinforcement learning to reason using chain of thought. These advanced reasoning capabilities provide new avenues for improving the safety and robustness of our models. In particular, our models can reason about our safety policies in context when responding to potentially unsafe prompts, through ...
OpenAI   +199 more
core   +5 more sources

Comparison of virulence gene profiles and genomic fingerprints of Vibrio cholerae O1 and non-O1/non-O139 isolates from diarrheal patients in southern Thailand

open access: yesTropical Medicine and Health, 2018
Background Vibrio cholerae is associated with severe watery diarrheal disease among people in many parts of the world, including the coastal provinces of Southern Thailand. There are relatively few studies focusing on the genetic characterization among V.
Sakrapee Tulatorn   +3 more
doaj   +2 more sources

O Serogroup-Specific Touchdown-Multiplex Polymerase Chain Reaction for Detection and Identification of Vibrio cholerae O1, O139, and Non-O1/Non-O139 [PDF]

open access: yesBiochemistry Research International, 2014
A novel, sensitive locus-specific touchdown-multiplex polymerase chain reaction (TMPCR), which is based on two-stage amplification pertaining to multiplex PCR and conditional touchdown strategy, was used in detecting and differentiating Vibrio cholerae ...
Adisak Bhumiratana   +5 more
doaj   +2 more sources

Cochleates derived from Vibrio cholerae O1 proteoliposomes : The impact of structure transformation on mucosal immunisation [PDF]

open access: yes, 2012
Cochleates are phospholipid-calcium precipitates derived from the interaction of anionic lipid vesicles with divalent cations. Proteoliposomes from bacteria may also be used as a source of negatively charged components, to induce calcium-cochleate ...
Perez, Jose L   +9 more
core   +4 more sources

Molecular characterization of Vibrio cholerae O1 and non-O1 from human and environmental sources in Malaysia [PDF]

open access: yes, 1999
A total of 31 strains of Vibrio cholerae O1 (10 from outbreak cases and 7 from surface water) and non-O1 (4 from clinical and 10 from surface water sources) isolated between 1993 and 1997 were examined with respect to presence of cholera enterotoxin (CT)
Elhadi, N.   +7 more
core   +4 more sources

Thermal model of water and CO activity of Comet C/1995 O1 (Hale-Bopp) [PDF]

open access: yes, 2011
An investigation of the activity of Comet C/1995 O1 (Hale-Bopp) with a thermophysical nucleus model that does not rely on the existence of amorphous ice is presented.
H.U. Keller   +8 more
core   +1 more source

Emerging trends in the etiology of enteric pathogens as evidenced from an active surveillance of hospitalized diarrhoeal patients in Kolkata, India [PDF]

open access: yes, 2010
Background: This study was conducted to determine the etiology of diarrhoea in a hospital setting in Kolkata. Active surveillance was conducted for 2 years on two random days per week by enrolling every fifth diarrhoeal patient admitted to the Infectious
Gopinath Nair   +35 more
core   +1 more source

Field evaluation of a rapid immunochromatographic dipstick test for the diagnosis of cholera in a high-risk population. [PDF]

open access: yes, 2006
BACKGROUND: Early detection of cholera outbreaks is crucial for the implementation of the most appropriate control strategies. METHODS: The performance of an immunochromatographic dipstick test (Institute Pasteur, Paris, France) specific for Vibrio ...
Park, T.   +47 more
core   +1 more source

O1-conotoxin Tx6.7 cloned from the genomic DNA of Conus textile that inhibits calcium currents

open access: yes, 2023
Background: Conotoxins exhibit great potential as neuropharmacology tools and therapeutic candidates due to their high affinity and specificity for ion channels, neurotransmitter receptors or transporters.
Manyi Yang (3722650)   +5 more
core   +1 more source

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